HitPredict

Interactor 1: H2AX (P16104)
Histone H2AX (H2a/x) (Histone H2A.X)
Gene: H2AX

Interactor 2: SMCA1 (P28370)
Probable global transcription activator SNF2L1 (EC 3.6.4.-) (ATP-dependent helicase SMARCA1) (Nucleosome-remodeling factor subunit SNF2L) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 1)
Gene: SMARCA1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	28242625
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Histone~SNF2-rel_dom
Common GO terms	GO:0003677 - DNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0042393 - histone binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 143 Hs			1 1054
+	Hs
		470278 H2A1_HUMAN (1-129): 7.56e-66: 197: 91.47		SMCA1_HUMAN (1-1054): 0: 1130: 100.00
+	Hs
		229296 H2AX_HUMAN (1-143): 3.71e-74: 219: 100.00		SMCA5_HUMAN (32-1051): 0: 1065: 81.86
+	Hs
		229433 H2A2B_HUMAN (1-128): 3.43e-66: 198: 92.97		SMCA5_HUMAN (32-1051): 0: 1065: 81.86
+	Hs
		229279 H2A1B_HUMAN (1-129): 8.35e-66: 197: 90.70		SMCA5_HUMAN (32-1051): 0: 1065: 81.86
+	Hs
		555466 H2AX_HUMAN (1-143): 3.71e-74: 219: 100.00		CHD4_HUMAN (29-960): 0: 789: 28.27
+	Hs
		1018640 H2A1H_HUMAN (1-128): 2.85e-66: 198: 92.19		CHD3_HUMAN (31-954): 0: 791: 28.94
+	Hs
		391675 H2A1B_HUMAN (1-129): 8.35e-66: 197: 90.70		CHD3_HUMAN (31-954): 0: 791: 28.94
+	Hs
		555654 H2AX_HUMAN (1-143): 3.71e-74: 219: 100.00		CHD8_HUMAN (2-1011): 0: 769: 27.72
+	Hs
		1059717 H2A2B_HUMAN (1-128): 3.43e-66: 198: 92.97		CHD4_HUMAN (29-960): 0: 789: 28.27
+	Hs
		1059795 H2A1H_HUMAN (1-128): 2.85e-66: 198: 92.19		CHD4_HUMAN (29-960): 0: 789: 28.27
+	Hs
		391704 H2A1B_HUMAN (1-129): 8.35e-66: 197: 90.70		CHD4_HUMAN (29-960): 0: 789: 28.27
+	Hs
		470387 H2A1_HUMAN (1-129): 7.56e-66: 197: 91.47		CHD4_HUMAN (29-960): 0: 789: 28.27
+	Hs
		391915 H2A1B_HUMAN (1-129): 8.35e-66: 197: 90.70		CHD8_HUMAN (2-1011): 0: 769: 27.72
+	Hs
		391728 H2A1B_HUMAN (1-129): 8.35e-66: 197: 90.70		CHD9_HUMAN (2-1019): 0: 741: 26.94
+	Hs
		151474 H2A1B_HUMAN (1-129): 8.35e-66: 197: 90.70		CHD2_HUMAN (21-1047): 0: 732: 29.60
+	Hs
		555359 H2AX_HUMAN (1-143): 3.71e-74: 219: 100.00		SMCA4_HUMAN (60-913): 0: 686: 31.42
+	Hs
		555532 H2AX_HUMAN (1-143): 3.71e-74: 219: 100.00		CHD1L_HUMAN (183-755): 2.35e-132: 424: 43.06
+	Hs
		555358 H2AX_HUMAN (1-143): 3.71e-74: 219: 100.00		SMCA2_HUMAN (170-669): 1.05e-122: 413: 44.32
+	Hs
		1151349 H2A2A_HUMAN (1-129): 7e-66: 197: 91.47		CHD1L_HUMAN (183-755): 2.35e-132: 424: 43.06
+	Hs
		1185203 H2A3_HUMAN (1-129): 5.88e-66: 197: 91.47		CHD1L_HUMAN (183-755): 2.35e-132: 424: 43.06