HitPredict - High confidence protein-protein interactions

Interactor 1: GROU (P16371)
Protein groucho (Enhancer of split m9/10 protein) (E(spl)m9/10)
Gene: gro

Interactor 2: GROU (P16371)
Protein groucho (Enhancer of split m9/10 protein) (E(spl)m9/10)
Gene: gro

Species: Drosophila melanogaster

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.76	1.00	0.873

Property	Details
Experiments	18034187, 19036929, 22319573, 15121853
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	TLE_N~TLE_N, WD40~WD40
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0003714 - transcription corepressor activity GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005667 - transcription regulator complex and 16 others more... GO:0006355 - regulation of DNA-templated transcription GO:0007173 - epidermal growth factor receptor signaling pathway GO:0007399 - nervous system development GO:0007541 - sex determination, primary response to X:A ratio GO:0008134 - transcription factor binding GO:0008293 - torso signaling pathway GO:0008543 - fibroblast growth factor receptor signaling pathway GO:0016055 - Wnt signaling pathway GO:0030154 - cell differentiation GO:0032991 - protein-containing complex GO:0045751 - negative regulation of Toll signaling pathway GO:0045892 - negative regulation of DNA-templated transcription GO:0071837 - HMG box domain binding GO:0071906 - CRD domain binding GO:0090090 - negative regulation of canonical Wnt signaling pathway GO:0140297 - DNA-binding transcription factor binding
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1	730
Dm

1	730

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Last updated: 15 Jul 2024