HitPredict

Interactor 1: FER (P16591)
Tyrosine-protein kinase Fer (EC 2.7.10.2) (Feline encephalitis virus-related kinase FER) (Fujinami poultry sarcoma/Feline sarcoma-related protein Fer) (Proto-oncogene c-Fer) (Tyrosine kinase 3) (p94-Fer)
Gene: FER

Interactor 2: PP1R7 (Q15435)
Protein phosphatase 1 regulatory subunit 7 (Protein phosphatase 1 regulatory subunit 22)
Gene: PPP1R7

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.55	1.00	0.743

Property	Details
Experiments	25814554, unassigned1126
Identification Methods	two hybrid, two hybrid array
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	LRR_4~PK_Tyr_Ser-Thr
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 822 Hs			1 360
+	At
		85365 IOS1_ARATH (2-816): 0: 645: 15.72		ERL1_ARATH (218-360): 5.84e-17: 84.5: 16.11
+	At
		1114699 IOS1_ARATH (2-816): 0: 645: 15.72		ERECT_ARATH (216-360): 3.03e-16: 82.2: 14.57
+	At
		1320745 IOS1_ARATH (2-816): 0: 645: 15.72		FLS2_ARATH (193-360): 7.98e-10: 62.5: 11.80
+	At
		1167625 IOS1_ARATH (2-816): 0: 645: 15.72		ERL2_ARATH (5-132): 1e-09: 62.1: 9.43
+	At
		84926 Y5169_ARATH (2-820): 6.72e-166: 504: 16.14		Y1723_ARATH (12-230): 1.15e-26: 113: 16.02
+	At
		85106 Y5596_ARATH (5-822): 1.39e-158: 486: 14.50		RGI2_ARATH (19-251): 3.3e-28: 118: 18.70
+	At
		286306 Y2899_ARATH (15-822): 6.95e-160: 489: 15.50		Y1723_ARATH (12-230): 1.15e-26: 113: 16.02
+	Hs
		433758 LYN_HUMAN (372-817): 5.02e-159: 474: 32.26		SCRIB_HUMAN (110-360): 8.96e-32: 128: 19.38
+	At
		85102 F4I065_ARATH (2-816): 4.95e-157: 482: 13.33		RGI2_ARATH (19-251): 3.3e-28: 118: 18.70
+	At
		95366 F4I065_ARATH (2-816): 4.95e-157: 482: 13.33		RGI4_ARATH (20-222): 1.13e-27: 116: 15.96
+	At
		84537 Y4245_ARATH (21-822): 1.08e-157: 484: 14.85		Y1723_ARATH (12-230): 1.15e-26: 113: 16.02
+	At
		83729 Y5182_ARATH (2-820): 2.3e-162: 496: 14.65		CLV1_ARATH (1-134): 1.36e-18: 89.1: 13.77
+	At
		95380 F4I065_ARATH (2-816): 4.95e-157: 482: 13.33		TDR_ARATH (10-224): 2.73e-21: 97.6: 12.61
+	At
		1258438 Q9SNA2_ARATH (5-822): 4.57e-159: 487: 16.36		MIK2_ARATH (166-360): 2.5e-18: 88.3: 18.41
+	At
		95375 F4I065_ARATH (2-816): 4.95e-157: 482: 13.33		MIK2_ARATH (166-360): 2.5e-18: 88.3: 18.41
+	At
		84531 Y4245_ARATH (21-822): 1.08e-157: 484: 14.85		IRK_ARATH (181-360): 1.57e-16: 82.9: 15.96
+	Hs
		433956 LYN_HUMAN (372-817): 5.02e-159: 474: 32.26		ERBIN_HUMAN (24-160): 1.95e-18: 89.1: 14.11
+	At
		1325021 Y5181_ARATH (5-822): 3.97e-161: 492: 15.17		PXL1_ARATH (36-137): 2.22e-12: 70.3: 16.82
+	At
		84525 Y4245_ARATH (21-822): 1.08e-157: 484: 14.85		RGI1_ARATH (192-359): 5.93e-14: 75.2: 16.28
+	Hs
		433876 LYN_HUMAN (372-817): 5.02e-159: 474: 32.26		CEP97_HUMAN (181-310): 3.01e-09: 60.5: 29.23