HitPredict

Interactor 1: AT2A2 (P16615)
Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 (SERCA2) (SR Ca(2+)-ATPase 2) (EC 7.2.2.10) (Calcium pump 2) (Calcium-transporting ATPase sarcoplasmic reticulum type, slow twitch skeletal muscle isoform) (Endoplasmic reticulum class 1/2 Ca(2+) ATPase)
Gene: ATP2A2

Interactor 2: GPR17 (Q13304)
Uracil nucleotide/cysteinyl leukotriene receptor (UDP/CysLT receptor) (G-protein coupled receptor 17) (P2Y-like receptor) (R12)
Gene: GPR17

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1042 Hs			1 367
+	Hs
		561517 AT2A2_HUMAN (1-1042): 0: 1060: 100.00		OPRD_HUMAN (11-365): 1.34e-74: 237: 23.90
+	Hs
		428908 AT2A2_HUMAN (1-1042): 0: 1060: 100.00		ADRB2_HUMAN (39-364): 4.53e-70: 226: 17.31
+	Hs
		561533 AT2A2_HUMAN (1-1042): 0: 1060: 100.00		CCR4_HUMAN (33-344): 9.2e-68: 219: 25.63
+	Hs
		1031036 AT2A3_HUMAN (1-997): 0: 956: 76.85		GPR17_HUMAN (1-367): 4.06e-90: 276: 100.00
+	Hs
		782452 AT2A3_HUMAN (1-997): 0: 956: 76.85		P2RY2_HUMAN (51-331): 2.74e-84: 262: 33.91
+	Hs
		849697 AT2A3_HUMAN (1-997): 0: 956: 76.85		CCR6_HUMAN (57-366): 1.61e-84: 262: 26.63
+	Hs
		561538 AT2A2_HUMAN (1-1042): 0: 1060: 100.00		PAR2_HUMAN (57-341): 1.38e-42: 154: 33.78
+	Hs
		561582 AT2A2_HUMAN (1-1042): 0: 1060: 100.00		P2RY6_HUMAN (92-343): 6.63e-33: 127: 35.85
+	Hs
		876172 AT2A3_HUMAN (1-997): 0: 956: 76.85		PAR2_HUMAN (57-341): 1.38e-42: 154: 33.78
+	Hs
		163777 AT2A1_HUMAN (1-1000): 0: 961: 83.72		CCR8_HUMAN (60-340): 2.15e-32: 126: 28.77
+	Hs
		1202701 AT2A3_HUMAN (1-997): 0: 956: 76.85		P2RY8_HUMAN (66-365): 1.26e-33: 129: 30.77
+	Hs
		530883 AT1A3_HUMAN (4-997): 0: 794: 26.55		GPR17_HUMAN (1-367): 4.06e-90: 276: 100.00
+	Hs
		530845 AT1A3_HUMAN (4-997): 0: 794: 26.55		P2RY2_HUMAN (51-331): 2.74e-84: 262: 33.91
+	Hs
		392982 AT1A1_HUMAN (3-997): 0: 797: 26.72		ADRB2_HUMAN (39-364): 4.53e-70: 226: 17.31
+	Hs
		530839 AT1A3_HUMAN (4-997): 0: 794: 26.55		NK3R_HUMAN (2-367): 7.33e-69: 225: 18.33
+	Hs
		530862 AT1A3_HUMAN (4-997): 0: 794: 26.55		CXCR4_HUMAN (28-340): 6.8e-70: 224: 23.27
+	Hs
		530844 AT1A3_HUMAN (4-997): 0: 794: 26.55		OPRX_HUMAN (17-357): 4.64e-67: 217: 22.35
+	Hs
		530861 AT1A3_HUMAN (4-997): 0: 794: 26.55		PAR2_HUMAN (57-341): 1.38e-42: 154: 33.78
+	Hs
		393214 AT1A1_HUMAN (3-997): 0: 797: 26.72		P2RY6_HUMAN (92-343): 6.63e-33: 127: 35.85
+	Hs
		530835 AT1A3_HUMAN (4-997): 0: 794: 26.55		PTAFR_HUMAN (61-336): 4.9e-34: 130: 29.07