HitPredict

Interactor 1: SPTCA (P13395)
Spectrin alpha chain
Gene: alpha-Spec

Interactor 2: FLII (Q24020)
Protein flightless-1 (Flightless-I)
Gene: FLII

Species: Drosophila melanogaster

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	38944040
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003779 - actin binding GO:0005509 - calcium ion binding GO:0051015 - actin filament binding
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 2415 Dm			1 1256
+	Hs
		1093305 CP250_HUMAN (331-2403): 3.45e-69: 262: 9.08		FLII_HUMAN (282-828): 1.24e-29: 130: 12.79
+	Hs
		224585 ACTN4_HUMAN (1821-2158): 1.76e-13: 78.6: 22.87		GELS_HUMAN (864-1251): 2.23e-80: 283: 16.99
+	Hs
		336402 SPTB2_HUMAN (5-1707): 1.15e-58: 228: 19.92		SVIL_HUMAN (510-875): 4.73e-20: 99.3: 19.25
+	Dm
		1028078 SPTCB_DROME (5-577): 9.95e-20: 99.8: 31.08		FLII_DROME (1-304): 1.09e-59: 227: 26.06
+	Hs
		1028850 SPTB2_HUMAN (5-1707): 1.15e-58: 228: 19.92		LRRC7_HUMAN (20-280): 2.85e-18: 93.6: 29.89
+	Dm
		1171759 Q9VZQ3_DROME (1-383): 3.68e-11: 71.6: 19.01		FLII_DROME (1-304): 1.09e-59: 227: 26.06
+	Hs
		336418 SPTN1_HUMAN (2-1232): 6.72e-45: 182: 21.48		SVIL_HUMAN (510-875): 4.73e-20: 99.3: 19.25
+	Hs
		336376 CENPF_HUMAN (1286-2402): 1.45e-29: 132: 8.90		SVIL_HUMAN (510-875): 4.73e-20: 99.3: 19.25
+	Hs
		336333 ACTN1_HUMAN (4-364): 2.81e-22: 107: 16.32		SVIL_HUMAN (510-875): 4.73e-20: 99.3: 19.25
+	Hs
		1399282 MACF1_HUMAN (477-2365): 5.17e-23: 110: 9.15		LRRC7_HUMAN (20-280): 2.85e-18: 93.6: 29.89
+	Hs
		224568 ACTN4_HUMAN (1821-2158): 1.76e-13: 78.6: 22.87		SVIL_HUMAN (510-875): 4.73e-20: 99.3: 19.25