Interactor 1: PLCG2 (P16885)
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 (EC 3.1.4.11) (Phosphoinositide phospholipase C-gamma-2) (Phospholipase C-IV) (PLC-IV) (Phospholipase C-gamma-2) (PLC-gamma-2)
Gene: PLCG2
Interactor 2: P85A (P27986)
Phosphatidylinositol 3-kinase regulatory subunit alpha (PI3-kinase regulatory subunit alpha) (PI3K regulatory subunit alpha) (PtdIns-3-kinase regulatory subunit alpha) (Phosphatidylinositol 3-kinase 85 kDa regulatory subunit alpha) (PI3-kinase subunit p85-alpha) (PtdIns-3-kinase regulatory subunit p85-alpha)
Gene: PIK3R1
Species: Homo sapiens
Source: intact
Category: High-throughput
Confidence: High
Method score | Annotation score | Interaction score |
---|---|---|
0.38 | 1.00 | 0.618 |
The method score is based on:
Property | Details |
---|---|
Experiments | 17474147 |
Identification Methods | peptide array |
Interaction Type | physical association |
The annotation score is based on:
Property | Details |
---|---|
Interacting Pfam domains | C2~SH2, PI3K_P85_iSH2~SH2, SH2~SH3_1 |
Common GO terms | GO:0001784 - phosphotyrosine residue binding GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0030183 - B cell differentiation and 2 others more... |
Homologous interactions | 4 |
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Last updated: 15 Jul 2024