HitPredict

Interactor 1: YBOX3 (P16989)
Y-box-binding protein 3 (Cold shock domain-containing protein A) (DNA-binding protein A) (Single-strand DNA-binding protein NF-GMB)
Gene: YBX3

Interactor 2: SRPK2 (P78362)
SRSF protein kinase 2 (EC 2.7.11.1) (SFRS protein kinase 2) (Serine/arginine-rich protein-specific kinase 2) (SR-protein-specific kinase 2) [Cleaved into: SRSF protein kinase 2 N-terminal; SRSF protein kinase 2 C-terminal]
Gene: SRPK2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.501

Property	Details
Experiments	26167880
Identification Methods	enzymatic study
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 372 Hs			1 688
+	Hs
		563181 YBOX3_HUMAN (1-372): 8.1e-79: 248: 100.00		SRPK1_HUMAN (27-688): 1.57e-125: 388: 53.22
+	Hs
		942744 LN28B_HUMAN (63-314): 9.71e-58: 190: 22.39		SRPK2_HUMAN (12-688): 3.2e-128: 397: 95.66
+	Hs
		931084 YBOX1_HUMAN (58-372): 1.88e-52: 178: 45.89		SRPK2_HUMAN (12-688): 3.2e-128: 397: 95.66
+	Hs
		942962 LN28A_HUMAN (82-256): 3.86e-42: 148: 25.82		SRPK2_HUMAN (12-688): 3.2e-128: 397: 95.66
+	Hs
		1302050 LN28A_HUMAN (82-256): 3.86e-42: 148: 25.82		SRPK1_HUMAN (27-688): 1.57e-125: 388: 53.22
+	Hs
		563018 YBOX3_HUMAN (1-372): 8.1e-79: 248: 100.00		CDK2_HUMAN (378-687): 1.93e-91: 288: 17.14
+	Hs
		563222 YBOX3_HUMAN (1-372): 8.1e-79: 248: 100.00		SRPK3_HUMAN (450-687): 1.19e-63: 223: 66.39
+	Hs
		850633 YBOX1_HUMAN (58-372): 1.88e-52: 178: 45.89		KS6A3_HUMAN (2-362): 2.51e-78: 266: 13.83
+	Hs
		931170 YBOX1_HUMAN (58-372): 1.88e-52: 178: 45.89		KS6A1_HUMAN (2-359): 1.19e-76: 262: 14.13
+	Hs
		834150 YBOX2_HUMAN (58-366): 4.54e-50: 173: 42.54		CLK3_HUMAN (62-240): 6.66e-62: 220: 31.11
+	Hs
		834124 LN28A_HUMAN (82-256): 3.86e-42: 148: 25.82		CLK3_HUMAN (62-240): 6.66e-62: 220: 31.11
+	Hs
		1047634 LN28A_HUMAN (82-256): 3.86e-42: 148: 25.82		CDK13_HUMAN (373-687): 1.6e-54: 204: 15.85
+	Hs
		1334573 LN28A_HUMAN (82-256): 3.86e-42: 148: 25.82		CDK12_HUMAN (291-687): 5.8e-54: 203: 13.17
+	Ce
		954344 P91306_CAEEL (78-233): 1.61e-41: 148: 39.49		SPK1_CAEEL (459-686): 8.03e-54: 201: 49.39
+	Dm
		1278931 Q95RE4_DROME (79-229): 1.33e-33: 129: 53.64		Q9VR61_DROME (69-348): 1.39e-36: 149: 15.39