Interactor 1: AT1A3 (P13637)
Sodium/potassium-transporting ATPase subunit alpha-3 (Na(+)/K(+) ATPase alpha-3 subunit) (EC 7.2.2.13) (Na(+)/K(+) ATPase alpha(III) subunit) (Sodium pump subunit alpha-3)
Gene: ATP1A3
Interactor 2: AT12A (P54707)
Potassium-transporting ATPase alpha chain 2 (HK alpha 2) (Non-gastric H(+)/K(+) ATPase subunit alpha) (EC 7.2.2.19) (Non-gastric Na(+)/K(+) ATPase subunit alpha) (EC 7.2.2.13) (Proton pump) (Sodium pump)
Gene: ATP12A
Species: Homo sapiens
Source: intact
Category: High-throughput
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.54 | 1.00 | 0.737 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 35575683, unassigned3799 |
| Identification Methods | cross-linking study, anti tag coimmunoprecipitation |
| Interaction Type | physical association, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | Cation_ATPase~E1-E2_ATPase, Cation_ATPase~Hydrolase, Cation_ATPase_C~Cation_ATPase_C, Cation_ATPase_C~E1-E2_ATPase, Cation_ATPase_C~Hydrolase, Cation_ATPase_N~E1-E2_ATPase, Cation_ATPase_N~Hydrolase, E1-E2_ATPase~E1-E2_ATPase, E1-E2_ATPase~Hydrolase |
| Common GO terms | GO:0005391 - P-type sodium:potassium-exchanging transporter activity GO:0005524 - ATP binding GO:0005886 - plasma membrane GO:0006883 - intracellular sodium ion homeostasis GO:0016887 - ATP hydrolysis activity and 5 others more... |
| Homologous interactions | 13 |
Homologous interactions
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Last updated: 11Aug2025
