HitPredict

Interactor 1: GYS1 (P13807)
Glycogen [starch] synthase, muscle (EC 2.4.1.11) (Glycogen synthase 1)
Gene: GYS1

Interactor 2: PPR3C (Q9UQK1)
Protein phosphatase 1 regulatory subunit 3C (Protein phosphatase 1 regulatory subunit 5) (PP1 subunit R5) (Protein targeting to glycogen) (PTG)
Gene: PPP1R3C

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.80	0.60	0.697

Property	Details
Experiments	26186194, 28514442, 28330616, 33961781
Identification Methods	affinity chromatography technology, pull down, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0005978 - glycogen biosynthetic process
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 737 Hs			1 317
+	Hs
		568668 GYS1_HUMAN (1-737): 0: 1422: 100.00		PPR3B_HUMAN (19-316): 4.9e-120: 348: 39.67
+	Hs
		932669 GYS2_HUMAN (1-658): 0: 1118: 72.53		PPR3C_HUMAN (1-317): 3.76e-162: 456: 100.00
+	Hs
		932668 GYS2_HUMAN (1-658): 0: 1118: 72.53		PPR3B_HUMAN (19-316): 4.9e-120: 348: 39.67
+	Sc
		692525 GYS2_YEAST (23-660): 0: 1061: 53.96		PIG1_YEAST (82-285): 7.9e-42: 154: 20.35
+	Ca
		1202843 Q5A850_CANAL (23-648): 0: 1083: 57.48		Q5A932_CANAL (169-277): 4.22e-29: 119: 24.46
+	Sc
		657172 GYS1_YEAST (23-660): 0: 1066: 54.49		GAC1_YEAST (158-275): 5.51e-32: 127: 29.85
+	Sc
		657188 GYS1_YEAST (23-660): 0: 1066: 54.49		GIP2_YEAST (166-256): 1.27e-31: 125: 36.74
+	Sc
		657190 GYS1_YEAST (23-660): 0: 1066: 54.49		PIG2_YEAST (166-280): 1.39e-31: 125: 29.92
+	Sc
		692484 GYS2_YEAST (23-660): 0: 1061: 53.96		GAC1_YEAST (158-275): 5.51e-32: 127: 29.85
+	Sc
		692509 GYS2_YEAST (23-660): 0: 1061: 53.96		GIP2_YEAST (166-256): 1.27e-31: 125: 36.74
+	Sc
		692511 GYS2_YEAST (23-660): 0: 1061: 53.96		PIG2_YEAST (166-280): 1.39e-31: 125: 29.92