Protein: MDHC
Malate dehydrogenase, cytoplasmic (EC 1.1.1.37)

Gene: MDHC, MDH2
Organism: Saccharomyces cerevisiae S288C
Interactions: 66
UniProt ID: P22133

Gene Ontology (top 5):
GO:0005737 - cytoplasm
GO:0005739 - mitochondrion
GO:0005829 - cytosol
GO:0006094 - gluconeogenesis
GO:0006099 - tricarboxylic acid cycle

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

604244

MDHC
Malate dehydrogenase, cytoplasmic

3

14

Small-scale

0.833

High

604259

GID4
Vacuolar import and degradation protein 24

3

1

Small-scale

0.662

High

604253

MDHP
Malate dehydrogenase, peroxisomal

1

14

Small-scale

0.621

High

567925

MDHM
Malate dehydrogenase, mitochondrial

1

14

Small-scale

0.618

High

604249

GID7
Glucose-induced degradation protein 7

2

2

Small-scale

0.595

High

604286

GET3
ATPase GET3

2

0

High-throughput

0.594

High

510267

SSB1
Ribosome-associated molecular chaperone SSB1

2

8

High-throughput

0.584

High

365795

HSP82
ATP-dependent molecular chaperone HSP82

2

8

High-throughput

0.571

High

490345

HSP71
Heat shock protein SSA1

2

5

High-throughput

0.552

High

604274

LCF4
Long-chain-fatty-acid--CoA ligase 4

1

1

High-throughput

0.536

High

604268

MET18
DNA repair/transcription protein MET18/MMS19

1

0

High-throughput

0.513

High

604269

YIK8
Putative zinc metalloproteinase YIL108W

1

0

High-throughput

0.513

High

604287

RPN5
26S proteasome regulatory subunit RPN5

1

0

High-throughput

0.513

High

604271

GST1
Glutathione S-transferase 1

1

1

High-throughput

0.508

High

604275

KPYK2
Pyruvate kinase 2

1

1

High-throughput

0.508

High

477126

UBI4P
Polyubiquitin [Cleaved into: Ubiquitin]

1

11

High-throughput

0.501

High

378285

LEU3
3-isopropylmalate dehydrogenase

1

5

High-throughput

0.500

High

427176

ILVB
Acetolactate synthase catalytic subunit, mitochondrial

1

1

High-throughput

0.500

High

454180

TBA1
Tubulin alpha-1 chain

1

3

High-throughput

0.500

High

543202

HSC82
ATP-dependent molecular chaperone HSC82

1

8

High-throughput

0.500

High

560562

BIP
Endoplasmic reticulum chaperone BiP

1

6

High-throughput

0.500

High

587931

HSP60
Heat shock protein 60, mitochondrial

1

3

High-throughput

0.500

High

604245

CLH
Clathrin heavy chain

1

2

High-throughput

0.500

High

604250

CDC48
Cell division control protein 48

1

7

High-throughput

0.500

High

604261

YHI0
Putative proline--tRNA ligase YHR020W

1

1

High-throughput

0.500

High

604265

MET10
Sulfite reductase [NADPH] flavoprotein component

1

1

High-throughput

0.500

High

572724

PDI
Protein disulfide-isomerase

1

4

High-throughput

0.489

High

604270

MGA2
Protein MGA2

1

0

High-throughput

0.486

High

448191

F16P
Fructose-1,6-bisphosphatase

1

0

Small-scale

0.480

High

393517

PMA1
Plasma membrane ATPase 1

1

0

High-throughput

0.479

High

423431

PUR2
Bifunctional purine biosynthetic protein ADE5,7 [Includes: Phosphoribosylamine--glycine ligase

1

0

High-throughput

0.479

High

498436

METK1
S-adenosylmethionine synthase 1

1

0

High-throughput

0.479

High

540024

GFA1
Glutamine--fructose-6-phosphate aminotransferase [isomerizing]

1

0

High-throughput

0.479

High

562180

PFKA1
ATP-dependent 6-phosphofructokinase subunit alpha

1

0

High-throughput

0.479

High

604248

SCJ1
DnaJ-related protein SCJ1

1

0

High-throughput

0.479

High

604252

URA7
CTP synthase 1

1

0

High-throughput

0.479

High

443970

CISY2
Citrate synthase, peroxisomal

1

5

High-throughput

0.479

High

604246

AATC
Aspartate aminotransferase, cytoplasmic

1

1

High-throughput

0.479

High

604254

CACP
Carnitine O-acetyltransferase, mitochondrial

1

1

High-throughput

0.479

High

604255

TOR1
Serine/threonine-protein kinase TOR1

1

2

Small-scale

0.479

High

604258

FAT2
Oxalate--CoA ligase

1

1

High-throughput

0.479

High

604262

KOG1
Target of rapamycin complex 1 subunit KOG1

1

4

Small-scale

0.479

High

604263

LYS1
Saccharopine dehydrogenase [NAD(+), L-lysine-forming]

1

1

High-throughput

0.479

High

604264

LCF2
Long-chain-fatty-acid--CoA ligase 2

1

1

High-throughput

0.479

High

604272

LST8
Target of rapamycin complex subunit LST8

1

1

Small-scale

0.479

High

604279

PIL1
Sphingolipid long chain base-responsive protein PIL1

1

2

High-throughput

0.479

High

604284

DCI1
Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase

1

4

High-throughput

0.479

High

604256

PMU1
Probable phosphoglycerate mutase PMU1

1

0

High-throughput

0.458

High

604257

KAE1
tRNA N6-adenosine threonylcarbamoyltransferase

1

0

High-throughput

0.458

High

604273

TOS3
Serine/threonine-protein kinase TOS3

1

0

High-throughput

0.458

High

604276

STR3
Cystathionine beta-lyase

1

0

High-throughput

0.458

High

604278

PEX8
Peroxisomal biogenesis factor 8

1

0

High-throughput

0.458

High

604288

PDP1
[Pyruvate dehydrogenase [acetyl-transferring]]-phosphatase 1, mitochondrial

1

0

High-throughput

0.458

High

604277

YG29
Uncharacterized protein YGR066C

1

1

Small-scale

0.457

High

604281

ACT
Actin

1

1

High-throughput

0.457

High

477902

HSP77
Import motor subunit, mitochondrial

1

9

High-throughput

0.445

High

604266

SSB2
Ribosome-associated molecular chaperone SSB2

1

8

High-throughput

0.445

High

604260

HXT5
Probable glucose transporter HXT5

1

1

High-throughput

0.437

High

604282

FOX2
Peroxisomal hydratase-dehydrogenase-epimerase

1

2

High-throughput

0.437

High

604283

MMS22
E3 ubiquitin-protein ligase substrate receptor MMS22

1

1

High-throughput

0.437

High

604247

EXG1
Glucan 1,3-beta-glucosidase I/II

1

0

High-throughput

0.279

Low

604267

RFC2
Replication factor C subunit 2

1

0

High-throughput

0.279

Low

604251

MGMT
Methylated-DNA--protein-cysteine methyltransferase

1

0

High-throughput

0.249

Low

604280

YG37
Uncharacterized protein YGR127W

1

0

High-throughput

0.249

Low

604285

TCO89
Target of rapamycin complex 1 subunit TCO89

1

0

Small-scale

0.249

Low


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Last updated: 15 Jul 2024