HitPredict

Interactor 1: PTN2 (P17706)
Tyrosine-protein phosphatase non-receptor type 2 (EC 3.1.3.48) (T-cell protein-tyrosine phosphatase) (TCPTP)
Gene: PTPN2

Interactor 2: C3AR (Q16581)
C3a anaphylatoxin chemotactic receptor (C3AR) (C3a-R)
Gene: C3AR1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 415 Hs			1 482
+	Hs
		573717 PTN1_HUMAN (4-413): 1e-158: 455: 51.93		C3AR_HUMAN (1-482): 1.62e-98: 306: 100.00
+	Hs
		570604 PTN2_HUMAN (1-415): 2.43e-175: 497: 100.00		C5AR2_HUMAN (20-183): 1.06e-39: 148: 39.16
+	Hs
		573956 PTN1_HUMAN (4-413): 1e-158: 455: 51.93		C5AR2_HUMAN (20-183): 1.06e-39: 148: 39.16
+	Hs
		573570 PTN1_HUMAN (4-413): 1e-158: 455: 51.93		C5AR1_HUMAN (294-482): 3.03e-38: 144: 27.60
+	Hs
		573596 PTN1_HUMAN (4-413): 1e-158: 455: 51.93		APJ_HUMAN (298-473): 1.89e-32: 129: 26.20
+	Hs
		665802 PTN6_HUMAN (2-351): 4.45e-132: 393: 27.78		SSR2_HUMAN (272-481): 1.11e-37: 143: 21.66
+	Hs
		665837 PTN6_HUMAN (2-351): 4.45e-132: 393: 27.78		CXCR4_HUMAN (322-457): 2.26e-36: 139: 23.78
+	Hs
		796449 PTN9_HUMAN (4-277): 3.68e-121: 365: 37.11		C5AR2_HUMAN (20-183): 1.06e-39: 148: 39.16
+	Hs
		783810 PTN9_HUMAN (4-277): 3.68e-121: 365: 37.11		CCR2_HUMAN (337-454): 4.23e-35: 136: 28.69
+	Hs
		441192 PTPRC_HUMAN (2-326): 8.27e-80: 269: 23.37		CXCR4_HUMAN (322-457): 2.26e-36: 139: 23.78
+	Hs
		895613 PTN11_HUMAN (32-272): 1.6e-47: 172: 39.00		CXCR4_HUMAN (322-457): 2.26e-36: 139: 23.78