HitPredict

Interactor 1: GFAP (P14136)
Glial fibrillary acidic protein (GFAP)
Gene: GFAP

Interactor 2: STK36 (Q9NRP7)
Serine/threonine-protein kinase 36 (EC 2.7.11.1) (Fused homolog)
Gene: STK36

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.44	0.60	0.515

Property	Details
Experiments	32814053
Identification Methods	two hybrid array, two hybrid pooling approach, validated two hybrid
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0042995 - cell projection
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 432 Hs			1 1315
+	Hs
		570363 GFAP_HUMAN (1-432): 3.97e-149: 432: 100.00		AKT1_HUMAN (1-325): 5.31e-125: 397: 29.43
+	Hs
		474504 VIME_HUMAN (16-431): 5.25e-137: 402: 57.28		AKT2_HUMAN (1-328): 1.74e-126: 401: 28.36
+	Hs
		474503 VIME_HUMAN (16-431): 5.25e-137: 402: 57.28		AKT1_HUMAN (1-325): 5.31e-125: 397: 29.43
+	Rn
		723751 VIME_RAT (38-431): 1.14e-133: 394: 59.90		AAPK1_RAT (1-539): 1.29e-124: 399: 19.89
+	Rn
		930582 K2C8_RAT (41-429): 6.44e-109: 331: 31.91		AAPK1_RAT (1-539): 1.29e-124: 399: 19.89
+	Rn
		930586 Q496Z5_RAT (49-428): 2.06e-105: 322: 57.07		AAPK1_RAT (1-539): 1.29e-124: 399: 19.89
+	Rn
		641295 PERI_RAT (49-428): 1.63e-103: 317: 56.92		AAPK1_RAT (1-539): 1.29e-124: 399: 19.89
+	Mm
		858172 AINX_MOUSE (37-387): 1.03e-80: 259: 49.72		BRSK2_MOUSE (4-644): 3.24e-144: 457: 21.04
+	Hs
		227217 KRT86_HUMAN (5-384): 3.2e-92: 288: 32.12		KCC2B_HUMAN (2-503): 1.16e-122: 397: 23.46
+	Rn
		660348 AINX_RAT (37-387): 1.23e-79: 256: 49.72		AAPK1_RAT (1-539): 1.29e-124: 399: 19.89
+	Hs
		1127803 K1H2_HUMAN (9-384): 1.02e-75: 244: 28.23		AKT3_HUMAN (1-327): 3.7e-126: 400: 28.44
+	Hs
		728234 K1H2_HUMAN (9-384): 1.02e-75: 244: 28.23		AKT1_HUMAN (1-325): 5.31e-125: 397: 29.43