HitPredict

Interactor 1: CHD7 (A2AJK6)
Chromodomain-helicase-DNA-binding protein 7 (CHD-7) (EC 3.6.4.12) (ATP-dependent helicase CHD7)
Gene: CHD7

Interactor 2: MTA2 (Q9R190)
Metastasis-associated protein MTA2 (Metastasis-associated 1-like 1)
Gene: MTA2

Species: Mus musculus

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	21532573
Identification Methods	anti bait coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003682 - chromatin binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0006338 - chromatin remodeling GO:0045944 - positive regulation of transcription by RNA polymerase II
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 2986 Mm			1 668
+	Hs
		296157 CHD7_HUMAN (1-2986): 0: 2602: 94.33		MTA2_HUMAN (1-668): 0: 728: 98.50
+	Mm
		57180 CHD7_MOUSE (1-2986): 0: 2659: 100.00		F8WHY8_MOUSE (1-668): 0: 665: 58.01
+	Hs
		1031963 CHD7_HUMAN (1-2986): 0: 2602: 94.33		MTA1_HUMAN (1-668): 0: 672: 55.83
+	Hs
		1350243 CHD7_HUMAN (1-2986): 0: 2602: 94.33		RCOR1_HUMAN (145-587): 9.22e-60: 210: 14.79
+	Hs
		229260 SMCA5_HUMAN (806-1870): 0: 897: 26.80		MTA2_HUMAN (1-668): 0: 728: 98.50
+	Hs
		296024 CHD4_HUMAN (681-1972): 0: 886: 27.17		MTA2_HUMAN (1-668): 0: 728: 98.50
+	Mm
		1125398 Q5DTP7_MOUSE (646-1972): 0: 877: 26.33		MTA2_MOUSE (1-668): 0: 735: 100.00
+	Mm
		1161082 CHD4_MOUSE (646-1972): 0: 875: 26.52		MTA2_MOUSE (1-668): 0: 735: 100.00
+	Hs
		295943 SMCA1_HUMAN (799-1853): 0: 881: 25.90		MTA2_HUMAN (1-668): 0: 728: 98.50
+	Hs
		295967 SMCA4_HUMAN (222-1594): 0: 880: 22.38		MTA2_HUMAN (1-668): 0: 728: 98.50
+	Hs
		229389 SMCA5_HUMAN (806-1870): 0: 897: 26.80		MTA1_HUMAN (1-668): 0: 672: 55.83
+	Hs
		1031857 CHD4_HUMAN (681-1972): 0: 886: 27.17		MTA1_HUMAN (1-668): 0: 672: 55.83
+	Hs
		658670 SMCA1_HUMAN (799-1853): 0: 881: 25.90		MTA1_HUMAN (1-668): 0: 672: 55.83
+	Hs
		229481 SMCA5_HUMAN (806-1870): 0: 897: 26.80		MTA3_HUMAN (1-567): 0: 643: 64.74
+	Hs
		1059835 CHD4_HUMAN (681-1972): 0: 886: 27.17		MTA3_HUMAN (1-567): 0: 643: 64.74
+	Hs
		658725 SMCA1_HUMAN (799-1853): 0: 881: 25.90		MTA3_HUMAN (1-567): 0: 643: 64.74
+	Mm
		56904 CHD5_MOUSE (525-1972): 0: 882: 24.27		MTA3_MOUSE (1-577): 0: 626: 63.76
+	Hs
		847013 SMCA4_HUMAN (222-1594): 0: 880: 22.38		RCOR2_HUMAN (134-651): 1.4e-72: 245: 16.02
+	Hs
		1059933 CHD4_HUMAN (681-1972): 0: 886: 27.17		RCOR1_HUMAN (145-587): 9.22e-60: 210: 14.79
+	Hs
		847110 SMCA4_HUMAN (222-1594): 0: 880: 22.38		RCOR1_HUMAN (145-587): 9.22e-60: 210: 14.79