Protein: RPB1
DNA-directed RNA polymerase II subunit RPB1 (RNA polymerase II subunit B1) (EC 2.7.7.6) (3'-5' exoribonuclease) (EC 3.1.13.-) (DNA-directed RNA polymerase II subunit A) (DNA-directed RNA polymerase III largest subunit) (RNA-directed RNA polymerase II subunit RPB1) (EC 2.7.7.48)

Gene: RPB1, Polr2a
Organism: Mus musculus
Interactions: 43
UniProt ID: P08775

Gene Ontology (top 5):
GO:0000791 - euchromatin
GO:0001046 - core promoter sequence-specific DNA binding
GO:0003677 - DNA binding
GO:0003899 - DNA-directed RNA polymerase activity
GO:0005634 - nucleus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

476234

NSD2
Histone-lysine N-methyltransferase NSD2

1

11

Small-scale

0.691

High

476252

EHMT2
Histone-lysine N-methyltransferase EHMT2

1

1

Small-scale

0.646

High

476221

SMCA4
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 4

1

8

Small-scale

0.618

High

476236

DIDO1
Death-inducer obliterator 1

1

4

Small-scale

0.618

High

476239

SMYD2
N-lysine methyltransferase SMYD2

1

2

Small-scale

0.618

High

476247

SMYD3
Histone-lysine N-methyltransferase SMYD3

1

2

Small-scale

0.618

High

476228

SRSF2
Serine/arginine-rich splicing factor 2

2

0

Small-scale

0.585

High

476245

CDK9
Cyclin-dependent kinase 9

2

12

Small-scale

0.584

High

476248

WWP2
NEDD4-like E3 ubiquitin-protein ligase WWP2

1

9

Small-scale

0.578

High

476223

EHMT1
Histone-lysine N-methyltransferase EHMT1

1

1

Small-scale

0.575

High

476225

ERR2
Steroid hormone receptor ERR2

1

5

High-throughput

0.554

High

476229

GPBP1
Vasculin

1

0

Small-scale

0.537

High

476230

HDAC4
Histone deacetylase 4

1

1

High-throughput

0.536

High

476231

SRSF1
Serine/arginine-rich splicing factor 1

1

3

Small-scale

0.515

High

476233

NANOG
Homeobox protein NANOG

1

0

High-throughput

0.513

High

476213

G3P
Glyceraldehyde-3-phosphate dehydrogenase

1

1

Small-scale

0.479

High

476216

CEBPA
CCAAT/enhancer-binding protein alpha

1

2

Small-scale

0.479

High

476220

NF1
Neurofibromin

1

1

Small-scale

0.479

High

476222

DDB1
DNA damage-binding protein 1

1

3

Small-scale

0.479

High

476226

DDX5
Probable ATP-dependent RNA helicase DDX5

1

3

Small-scale

0.479

High

476240

ELF5
ETS-related transcription factor Elf-5

1

1

High-throughput

0.479

High

476241

HNRPU
Heterogeneous nuclear ribonucleoprotein U

1

3

Small-scale

0.479

High

476244

EED
Polycomb protein EED

1

5

High-throughput

0.479

High

476251

RECQ1
ATP-dependent DNA helicase Q1

1

9

Small-scale

0.479

High

476237

ELOA1
Elongin-A

1

1

Small-scale

0.470

High

476219

EYA3
Protein phosphatase EYA3

1

0

High-throughput

0.460

High

378463

IL1A
Interleukin-1 alpha

1

0

Small-scale

0.458

High

476212

IRF1
Interferon regulatory factor 1

1

0

Small-scale

0.458

High

476232

KDM1A
Lysine-specific histone demethylase 1A

1

0

High-throughput

0.458

High

476246

FOXP3
Forkhead box protein P3

1

0

High-throughput

0.458

High

476215

CENPC
Centromere protein C

1

3

High-throughput

0.445

High

476218

WDR5
WD repeat-containing protein 5

1

2

Small-scale

0.445

High

476227

HIRA
Protein HIRA

1

3

Small-scale

0.445

High

476238

TAD2A
Transcriptional adapter 2-alpha

1

4

High-throughput

0.445

High

476243

ASH2L
Set1/Ash2 histone methyltransferase complex subunit ASH2

1

1

Small-scale

0.445

High

476249

KAT2A
Histone acetyltransferase KAT2A

1

8

High-throughput

0.445

High

476250

AIRE
Autoimmune regulator

1

5

Small-scale

0.445

High

449227

TNFA
Tumor necrosis factor

1

1

Small-scale

0.437

High

476224

LEO1
RNA polymerase-associated protein LEO1

1

2

Small-scale

0.437

High

476235

A16L1
Autophagy-related protein 16-1

1

7

High-throughput

0.437

High

476242

SATB2
DNA-binding protein SATB2

1

0

Small-scale

0.426

High

476217

RUVB1
RuvB-like 1

1

9

Small-scale

0.407

High

476214

CXL10
C-X-C motif chemokine 10

1

0

Small-scale

0.249

Low


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Last updated: 11Aug2025