HitPredict

Interactor 1: LEG3 (P17931)
Galectin-3 (Gal-3) (35 kDa lectin) (Carbohydrate-binding protein 35) (CBP 35) (Galactose-specific lectin 3) (Galactoside-binding protein) (GALBP) (IgE-binding protein) (L-31) (Laminin-binding protein) (Lectin L-29) (Mac-2 antigen)
Gene: LGALS3

Interactor 2: S12A7 (Q9Y666)
Solute carrier family 12 member 7 (Electroneutral potassium-chloride cotransporter 4) (K-Cl cotransporter 4)
Gene: SLC12A7

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.60	0.667

Property	Details
Experiments	26186194, 28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 250 Hs			1 1083
+	Hs
		572481 LEG3_HUMAN (1-250): 3.29e-96: 283: 100.00		S12A4_HUMAN (1-1083): 0: 1105: 69.48
+	Hs
		572474 LEG3_HUMAN (1-250): 3.29e-96: 283: 100.00		S12A6_HUMAN (14-1083): 0: 1102: 69.47
+	Hs
		815062 LEG7_HUMAN (115-247): 3.1e-45: 149: 35.04		S12A7_HUMAN (1-1083): 0: 1174: 100.00
+	Hs
		449398 LEG1_HUMAN (125-247): 3.18e-43: 144: 28.00		S12A7_HUMAN (1-1083): 0: 1174: 100.00
+	Hs
		119583 LEG9_HUMAN (108-249): 3.89e-40: 143: 37.67		S12A7_HUMAN (1-1083): 0: 1174: 100.00
+	Hs
		121236 LEG8_HUMAN (105-245): 4.74e-39: 139: 36.11		S12A7_HUMAN (1-1083): 0: 1174: 100.00
+	Hs
		119565 LEG9_HUMAN (108-249): 3.89e-40: 143: 37.67		S12A4_HUMAN (1-1083): 0: 1105: 69.48
+	Hs
		449377 LEG1_HUMAN (125-247): 3.18e-43: 144: 28.00		S12A6_HUMAN (14-1083): 0: 1102: 69.47
+	Hs
		119555 LEG9_HUMAN (108-249): 3.89e-40: 143: 37.67		S12A6_HUMAN (14-1083): 0: 1102: 69.47
+	Hs
		121232 LEG8_HUMAN (105-245): 4.74e-39: 139: 36.11		S12A4_HUMAN (1-1083): 0: 1105: 69.48
+	Hs
		121226 LEG8_HUMAN (105-245): 4.74e-39: 139: 36.11		S12A6_HUMAN (14-1083): 0: 1102: 69.47
+	Hs
		572325 LEG3_HUMAN (1-250): 3.29e-96: 283: 100.00		S12A2_HUMAN (25-1083): 0: 746: 20.65
+	Hs
		119282 LEG9_HUMAN (108-249): 3.89e-40: 143: 37.67		S12A2_HUMAN (25-1083): 0: 746: 20.65
+	Hs
		121133 LEG8_HUMAN (105-245): 4.74e-39: 139: 36.11		S12A2_HUMAN (25-1083): 0: 746: 20.65
+	Hs
		572442 LEG3_HUMAN (1-250): 3.29e-96: 283: 100.00		S12A9_HUMAN (116-911): 1.32e-167: 518: 24.88
+	Hs
		119512 LEG9_HUMAN (108-249): 3.89e-40: 143: 37.67		S12A9_HUMAN (116-911): 1.32e-167: 518: 24.88
+	Hs
		121209 LEG8_HUMAN (105-245): 4.74e-39: 139: 36.11		S12A9_HUMAN (116-911): 1.32e-167: 518: 24.88
+	Hs
		572323 LEG3_HUMAN (1-250): 3.29e-96: 283: 100.00		CTR2_HUMAN (160-603): 3.52e-94: 316: 16.18
+	Hs
		119269 LEG9_HUMAN (108-249): 3.89e-40: 143: 37.67		CTR2_HUMAN (160-603): 3.52e-94: 316: 16.18
+	Hs
		119196 LEG9_HUMAN (108-249): 3.89e-40: 143: 37.67		CTR1_HUMAN (160-603): 5.38e-87: 295: 14.35