Protein: MED8
Mediator of RNA polymerase II transcription subunit 8 (Mediator complex subunit 8)

Gene: MED8, mdt-8
Organism: Caenorhabditis elegans
Interactions: 45
UniProt ID: Q9U1W2

Gene Ontology (top 5):
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0003712 - transcription coregulator activity
GO:0006357 - regulation of transcription by RNA polymerase II
GO:0016592 - mediator complex
GO:0070847 - core mediator complex

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

185202

O18173
PAW domain-containing protein

1

1

High-throughput

0.512

High

108008

MDL1
Mad-like protein 1

1

2

High-throughput

0.508

High

108129

HIF1
Hypoxia-inducible factor 1

1

1

High-throughput

0.508

High

137572

NHR62
Nuclear hormone receptor family member nhr-62

1

5

High-throughput

0.508

High

784569

NHR23
Nuclear hormone receptor family member nhr-23

1

2

High-throughput

0.508

High

1088805

NHR47
Nuclear hormone receptor family member nhr-47

1

10

High-throughput

0.508

High

1090292

MXL3
Protein mxl-3

1

2

High-throughput

0.508

High

1090821

Q19496
Nuclear Hormone Receptor family

1

6

High-throughput

0.508

High

1341827

NHR5
Nuclear hormone receptor family member nhr-5

1

9

High-throughput

0.508

High

1341858

Q9NAE4
BZIP domain-containing protein

1

1

High-throughput

0.508

High

102035

APTF2
Transcription factor aptf-2

1

0

High-throughput

0.486

High

184257

FOXO
Forkhead box protein O

1

0

High-throughput

0.486

High

447579

MEC3
Mechanosensory protein 3

1

0

High-throughput

0.486

High

1090010

HM43
Homeobox protein ceh-43

1

0

High-throughput

0.486

High

1090547

UNC98
Zinc finger protein unc-98

1

0

High-throughput

0.486

High

1090772

ZTF2
Zinc finger protein ztf-2

1

0

High-throughput

0.486

High

1090948

Q19807
C2H2-type domain-containing protein

1

0

High-throughput

0.486

High

1095074

PAT9
Zinc finger protein pat-9

1

0

High-throughput

0.486

High

1125982

NFI1
Nuclear factor I family protein

1

0

High-throughput

0.486

High

1341693

UNC62
Homeobox protein unc-62

1

0

High-throughput

0.486

High

1353422

Q9TXN8
DM domain-containing protein

1

0

High-throughput

0.486

High

1182869

Q7KX66
Nuclear receptor domain-containing protein

1

8

High-throughput

0.481

High

184806

EYA1
Eyes absent homolog 1

1

1

High-throughput

0.464

High

1089911

FLH2
FLYWCH transcription factor 2

1

1

High-throughput

0.464

High

109793

H2KZA1
Nuclear hormone receptor E75

1

5

High-throughput

0.457

High

137311

SWIC2
SWI/SNF chromatin-remodeling accessory subunit 2

1

1

High-throughput

0.445

High

106608

G5EE45
BZIP domain-containing protein

1

1

High-throughput

0.439

High

954161

HMP1
Alpha-catenin-like protein hmp-1

1

1

High-throughput

0.439

High

1149493

Q6AHQ8
SH3 domain-containing protein

1

1

High-throughput

0.439

High

1197248

Q86DC0
SAM domain-containing protein

1

1

High-throughput

0.439

High

1211930

Q8I7K9
LIn-26 Related

1

1

High-throughput

0.439

High

60948

A5JYX3
Vinculin

1

1

High-throughput

0.417

High

104097

G5EBR0
LIR-1A protein

1

1

High-throughput

0.417

High

1000137

Q09989
SH3 domain-containing protein

1

1

High-throughput

0.417

High

1090232

Q18662
Caskin-2

1

1

High-throughput

0.417

High

1353566

Q9U1S5
BZIP domain-containing protein

1

1

High-throughput

0.417

High

1353581

FLH1
FLYWCH transcription factor 1

1

1

High-throughput

0.417

High

1353445

Q9TZ50
CCDC92/74 N-terminal domain-containing protein

1

0

High-throughput

0.292

High

1353582

F161
Protein fam-161

1

0

High-throughput

0.282

High

1090066

Q18426
TPR_REGION domain-containing protein

1

0

High-throughput

0.265

Low

1090563

Q19212
RasGEF domain protein

1

0

High-throughput

0.265

Low

1341556

Q9N3H6
RING-type domain-containing protein

1

0

High-throughput

0.265

Low

1353580

MOE3
CCCH-type zinc finger protein moe-3

1

0

High-throughput

0.265

Low

219419

O44490
ELKS/RAB6-interacting/CAST family member 2

1

0

High-throughput

0.249

Low

1353219

Q9TXM1
Uncharacterized protein

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024