HitPredict

Interactor 1: RSMB (P14678)
Small nuclear ribonucleoprotein-associated proteins B and B' (snRNP-B) (Sm protein B/B') (Sm-B/B') (SmB/B')
Gene: SNRPB

Interactor 2: PRP8 (Q6P2Q9)
Pre-mRNA-processing-splicing factor 8 (220 kDa U5 snRNP-specific protein) (PRP8 homolog) (Splicing factor Prp8) (p220)
Gene: PRPF8

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.88 1.00 0.940

The method score is based on:

Property Details
Experiments 28515276, 34079125, 17353931, 33961781, 35271311, unassigned3799
Identification Methods affinity chromatography technology, proximity labelling technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains LSM~PRP8_domainIV
Common GO terms GO:0000398 - mRNA splicing, via spliceosome
GO:0003723 - RNA binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005682 - U5 snRNP
and 5 others

more...
Homologous interactions 2

Homologous interactions

Color coding for hit scores

1 240
Hs

1 2335
+ Hs
+ Sc

Service provided by Combinatics, Japan

Last updated: 11Aug2025