HitPredict

Interactor 1: VINC (P18206)
Vinculin (Metavinculin) (MV)
Gene: VCL

Interactor 2: PKHA7 (Q6IQ23)
Pleckstrin homology domain-containing family A member 7 (PH domain-containing family A member 7)
Gene: PLEKHA7

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	28877994
Identification Methods	anti bait coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0005915 - zonula adherens GO:0070062 - extracellular exosome GO:0090136 - epithelial cell-cell adhesion
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 1134 Hs			1 1121
+	Hs
		575851 VINC_HUMAN (1-1134): 0: 893: 100.00		PKHA5_HUMAN (11-1074): 3.5e-95: 330: 29.45
+	Hs
		575783 VINC_HUMAN (1-1134): 0: 893: 100.00		RHG24_HUMAN (163-802): 1.1e-49: 191: 13.32
+	Hs
		716717 CTNA1_HUMAN (5-899): 1.05e-65: 241: 15.48		PKHA7_HUMAN (1-1121): 2.81e-180: 560: 100.00
+	Hs
		716775 CTNA1_HUMAN (5-899): 1.05e-65: 241: 15.48		PKHA5_HUMAN (11-1074): 3.5e-95: 330: 29.45
+	Hs
		716811 CTNA1_HUMAN (5-899): 1.05e-65: 241: 15.48		PKHA6_HUMAN (107-951): 1.85e-57: 218: 27.16
+	Hs
		640737 CTNA2_HUMAN (5-805): 6.26e-76: 272: 16.03		PKHA4_HUMAN (113-465): 8.31e-38: 154: 28.84
+	Hs
		716638 CTNA1_HUMAN (5-899): 1.05e-65: 241: 15.48		AFAD_HUMAN (329-1063): 1.33e-45: 182: 11.19
+	Hs
		716770 CTNA1_HUMAN (5-899): 1.05e-65: 241: 15.48		PKHA4_HUMAN (113-465): 8.31e-38: 154: 28.84
+	Hs
		1336131 TLN1_HUMAN (33-1112): 2.04e-52: 204: 12.22		SMUF1_HUMAN (4-213): 3.11e-48: 187: 18.58
+	Hs
		1331713 TLN1_HUMAN (33-1112): 2.04e-52: 204: 12.22		PKHA4_HUMAN (113-465): 8.31e-38: 154: 28.84