HitPredict

Interactor 1: PLAK (P14923)
Junction plakoglobin (Catenin gamma) (Desmoplakin III) (Desmoplakin-3)
Gene: JUP

Interactor 2: MCM2 (P49736)
DNA replication licensing factor MCM2 (EC 3.6.4.12) (Minichromosome maintenance protein 2 homolog) (Nuclear protein BM28)
Gene: MCM2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	25963833
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 745 Hs			1 904
+	Hs
		764542 CTNB1_HUMAN (1-731): 3.13e-172: 515: 67.38		MCM2_HUMAN (1-904): 0: 1078: 100.00
+	Hs
		254084 CTND1_HUMAN (203-728): 3.16e-90: 305: 16.25		MCM2_HUMAN (1-904): 0: 1078: 100.00
+	Hs
		577642 PLAK_HUMAN (1-745): 0: 550: 100.00		MCM5_HUMAN (169-902): 0: 768: 29.43
+	Hs
		755836 CTNB1_HUMAN (1-731): 3.13e-172: 515: 67.38		MCM5_HUMAN (169-902): 0: 768: 29.43
+	Hs
		577643 PLAK_HUMAN (1-745): 0: 550: 100.00		MCM7_HUMAN (188-886): 0: 707: 27.35
+	Hs
		887853 IMA1_HUMAN (270-664): 9.2e-48: 179: 14.32		MCM2_HUMAN (1-904): 0: 1078: 100.00
+	Hs
		253599 IMA7_HUMAN (266-685): 6.6e-45: 171: 15.27		MCM2_HUMAN (1-904): 0: 1078: 100.00
+	Hs
		179033 IMA6_HUMAN (273-659): 1.01e-40: 159: 13.95		MCM2_HUMAN (1-904): 0: 1078: 100.00
+	Dm
		616613 ARM_DROME (2-730): 2.02e-160: 487: 60.33		MCM5_DROME (195-902): 0: 745: 30.39
+	Hs
		756104 CTNB1_HUMAN (1-731): 3.13e-172: 515: 67.38		MCM7_HUMAN (188-886): 0: 707: 27.35
+	Hs
		254068 CTND1_HUMAN (203-728): 3.16e-90: 305: 16.25		MCM7_HUMAN (188-886): 0: 707: 27.35
+	At
		103714 IMPA1_ARATH (270-681): 2.92e-47: 177: 16.38		MCM6_ARATH (183-900): 0: 722: 27.87
+	At
		102310 IMPA2_ARATH (354-736): 1.63e-31: 131: 13.60		MCM6_ARATH (183-900): 0: 722: 27.87