HitPredict

Interactor 1: NELFE (P18615)
Negative elongation factor E (NELF-E) (RNA-binding protein RD)
Gene: NELFE

Interactor 2: NELFA (Q9H3P2)
Negative elongation factor A (NELF-A) (Wolf-Hirschhorn syndrome candidate 2 protein)
Gene: NELFA

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.94	0.60	0.753

The method score is based on:

Property	Details
Experiments	26186194, 26496610, 28514442, 12612062, 24981860, 33961781, 20305087
Identification Methods	affinity chromatography technology, pull down, anti tag coimmunoprecipitation, tandem affinity purification
Interaction Type	physical association, direct interaction, association

The annotation score is based on:

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003682 - chromatin binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0016604 - nuclear body GO:0031401 - positive regulation of protein modification process and 3 others more... GO:0032021 - NELF complex GO:0034244 - negative regulation of transcription elongation by RNA polymerase II GO:0045944 - positive regulation of transcription by RNA polymerase II
Homologous interactions	1

Homologous interactions

Color coding for hit scores

	1	380
Hs

1	528

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024