HitPredict

Interactor 1: RCC1 (P18754)
Regulator of chromosome condensation (Cell cycle regulatory protein) (Chromosome condensation protein 1)
Gene: RCC1

Interactor 2: FOXA1 (P55317)
Hepatocyte nuclear factor 3-alpha (HNF-3-alpha) (HNF-3A) (Forkhead box protein A1) (Transcription factor 3A) (TCF-3A)
Gene: FOXA1

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	25609649, 27926873
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000785 - chromatin GO:0003682 - chromatin binding GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 421 Hs			1 472
+	Hs
		578454 RCC1_HUMAN (1-421): 5.38e-164: 469: 100.00		FOXI2_HUMAN (66-377): 4.84e-47: 167: 29.65
+	Hs
		578471 RCC1_HUMAN (1-421): 5.38e-164: 469: 100.00		FOXB1_HUMAN (159-439): 8.56e-45: 161: 32.74
+	Hs
		578478 RCC1_HUMAN (1-421): 5.38e-164: 469: 100.00		FOXQ1_HUMAN (69-459): 1.06e-43: 160: 24.75
+	Ce
		184232 RCC1_CAEEL (3-364): 5.82e-43: 160: 17.65		FOXO_CAEEL (114-454): 2e-44: 165: 16.67
+	Hs
		1021174 RCC2_HUMAN (1-190): 1.36e-18: 89.7: 18.84		FOXC1_HUMAN (130-457): 7.84e-49: 177: 31.42