Interactor 1: H7C560 (H7C560)
non-specific serine/threonine protein kinase (EC 2.7.11.1)
Gene: BRAF

Interactor 2: 1433E (P62258)
14-3-3 protein epsilon (14-3-3E)
Gene: YWHAE

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.33 1.00 0.575

The method score is based on:

Property Details
Experiments 35271311
Identification Methods anti tag coimmunoprecipitation
Interaction Type association

The annotation score is based on:

Property Details
Interacting Pfam domains 14-3-3~C1_1, 14-3-3~PK_Tyr_Ser-Thr, 14-3-3~RBD
Common GO terms GO:0005829 - cytosol
GO:0007165 - signal transduction
Homologous interactions 12

Homologous interactions

Color coding for hit scores

1 767
Hs

1 255
+ Hs
+ Gg
+ Mm
+ Hs
+ Hs
+ At
+ Dm
+ At
+ Mm
+ At
+ Hs
+ Hs

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Last updated: 11Aug2025