HitPredict

Interactor 1: HSC82 (P15108)
ATP-dependent molecular chaperone HSC82 (82 kDa heat shock cognate protein) (Heat shock protein Hsp90 constitutive isoform)
Gene: HSC82

Interactor 2: PRR1 (P28708)
Serine/threonine-protein kinase PRR1 (EC 2.7.11.1) (Pheromone response regulator 1)
Gene: PRR1

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	37295430
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	HSP90~Pkinase
Common GO terms	GO:0005524 - ATP binding GO:0005737 - cytoplasm
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 705 Sc			1 518
+	Sc
		392357 HSP82_YEAST (1-705): 0: 963: 95.63		PRR1_YEAST (1-518): 4.56e-138: 410: 100.00
+	Sc
		393118 HSP82_YEAST (1-705): 0: 963: 95.63		FPK1_YEAST (12-515): 8.65e-109: 345: 20.31
+	Zm
		35603 A0A1D6LMW9_MAIZE (2-680): 0: 828: 47.53		A0A1D6QH07_MAIZE (181-517): 1.03e-111: 340: 19.66
+	Hs
		468758 HS90B_HUMAN (5-705): 0: 1016: 61.15		TSSK6_HUMAN (256-458): 1.23e-24: 105: 33.33
+	Hs
		468215 HS90B_HUMAN (5-705): 0: 1016: 61.15		AAPK2_HUMAN (256-446): 3.56e-22: 101: 34.03
+	Hs
		468784 HS90B_HUMAN (5-705): 0: 1016: 61.15		NUAK2_HUMAN (256-446): 6.9e-22: 101: 34.03
+	Hs
		461889 HS90A_HUMAN (4-705): 0: 1007: 60.67		TSSK6_HUMAN (256-458): 1.23e-24: 105: 33.33
+	Hs
		461308 HS90A_HUMAN (4-705): 0: 1007: 60.67		AAPK2_HUMAN (256-446): 3.56e-22: 101: 34.03
+	Hs
		461915 HS90A_HUMAN (4-705): 0: 1007: 60.67		NUAK2_HUMAN (256-446): 6.9e-22: 101: 34.03