Protein: NUAK2
NUAK family SNF1-like kinase 2 (EC 2.7.11.1) (Omphalocele kinase 2) (SNF1/AMP kinase-related kinase) (SNARK)

Gene: NUAK2
Organism: Homo sapiens
Interactions: 56
UniProt ID: Q9H093

Gene Ontology (top 5):
GO:0000287 - magnesium ion binding
GO:0004674 - protein serine/threonine kinase activity
GO:0005524 - ATP binding
GO:0006468 - protein phosphorylation
GO:0006915 - apoptotic process

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

692128

MARK3
MAP/microtubule affinity-regulating kinase 3

2

17

High-throughput

0.811

High

171323

MYPT1
Protein phosphatase 1 regulatory subunit 12A

4

6

High-throughput

0.805

High

461915

HS90A
Heat shock protein HSP 90-alpha

2

16

Small-scale

0.737

High

1420039

PP12C
Protein phosphatase 1 regulatory subunit 12C

2

6

High-throughput

0.694

High

1429600

RAI14
Ankycorbin

2

6

High-throughput

0.694

High

1270519

MARK2
Serine/threonine-protein kinase MARK2

1

17

High-throughput

0.691

High

995257

CSK2B
Casein kinase II subunit beta

1

0

High-throughput

0.656

High

349235

LATS1
Serine/threonine-protein kinase LATS1

1

13

Small-scale

0.647

High

1429601

FBW1B
F-box/WD repeat-containing protein 11

4

7

Small-scale

0.630

High

1429604

FBW1A
F-box/WD repeat-containing protein 1A

4

7

Small-scale

0.630

High

1399422

AGAP3
Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 3

1

1

High-throughput

0.618

High

1429597

TARA
TRIO and F-actin-binding protein

1

9

High-throughput

0.618

High

468784

HS90B
Heat shock protein HSP 90-beta

1

17

High-throughput

0.618

High

1095453

AAPK1
5'-AMP-activated protein kinase catalytic subunit alpha-1

1

17

Small-scale

0.618

High

1328761

LZTR1
Leucine-zipper-like transcriptional regulator 1

3

3

High-throughput

0.604

High

423121

A4
Amyloid-beta precursor protein

2

3

High-throughput

0.602

High

971981

1433E
14-3-3 protein epsilon

2

19

High-throughput

0.584

High

1202028

H90B3
Putative heat shock protein HSP 90-beta-3

1

18

High-throughput

0.575

High

320773

UBXN7
UBX domain-containing protein 7

2

1

High-throughput

0.574

High

1125395

FLNC
Filamin-C

2

6

High-throughput

0.574

High

1393313

SAHH3
Adenosylhomocysteinase 3

2

3

High-throughput

0.574

High

1395142

DCAF5
DDB1- and CUL4-associated factor 5

2

9

High-throughput

0.574

High

730875

1433S
14-3-3 protein sigma

2

20

High-throughput

0.558

High

1196317

GRAP1
GRIP1-associated protein 1

2

8

High-throughput

0.553

High

230105

SAHH2
S-adenosylhomocysteine hydrolase-like protein 1

1

3

High-throughput

0.536

High

872021

PI42A
Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha

1

2

High-throughput

0.536

High

1247474

SHC4
SHC-transforming protein 4

1

2

High-throughput

0.536

High

1429605

E41L3
Band 4.1-like protein 3

1

8

High-throughput

0.536

High

1158529

CDC37
Hsp90 co-chaperone Cdc37

1

2

Small-scale

0.514

High

1250776

MPRIP
Myosin phosphatase Rho-interacting protein

1

10

High-throughput

0.514

High

1429180

LACRT
Extracellular glycoprotein lacritin

1

0

High-throughput

0.513

High

158877

AP3D1
AP-3 complex subunit delta-1

1

2

High-throughput

0.489

High

217515

E41L2
Band 4.1-like protein 2

1

7

High-throughput

0.489

High

968438

PP1B
Serine/threonine-protein phosphatase PP1-beta catalytic subunit

1

8

High-throughput

0.489

High

1105088

TCOF
Treacle protein

1

1

High-throughput

0.489

High

1314835

ERF3B
Eukaryotic peptide chain release factor GTP-binding subunit ERF3B

1

4

High-throughput

0.489

High

1364928

AP3S1
AP-3 complex subunit sigma-1

1

1

High-throughput

0.489

High

1371524

USP9X
Ubiquitin carboxyl-terminal hydrolase 9X

1

8

High-throughput

0.489

High

1371675

UBP7
Ubiquitin carboxyl-terminal hydrolase 7

1

8

High-throughput

0.489

High

1402515

NEB2
Neurabin-2

1

12

High-throughput

0.489

High

1429599

WDR6
tRNA

1

12

High-throughput

0.489

High

1429602

NEB1
Neurabin-1

1

7

High-throughput

0.489

High

1429603

SRRM2
Serine/arginine repetitive matrix protein 2

1

3

High-throughput

0.489

High

990711

1433Z
14-3-3 protein zeta/delta

1

20

High-throughput

0.479

High

1045749

TF65
Transcription factor p65

1

2

High-throughput

0.479

High

1049762

1433F
14-3-3 protein eta

1

20

High-throughput

0.437

High

1138033

TNIP1
TNFAIP3-interacting protein 1

1

8

High-throughput

0.407

High

1290298

KBTB6
Kelch repeat and BTB domain-containing protein 6

1

2

High-throughput

0.407

High

1358851

KBTB7
Kelch repeat and BTB domain-containing protein 7

1

2

High-throughput

0.407

High

1393406

NAF1
H/ACA ribonucleoprotein complex non-core subunit NAF1

2

0

High-throughput

0.313

High

1248076

FIP1
Pre-mRNA 3'-end-processing factor FIP1

1

0

High-throughput

0.279

Low

1346632

VANG1
Vang-like protein 1

1

0

High-throughput

0.279

Low

1413974

MMTA2
Multiple myeloma tumor-associated protein 2

1

0

High-throughput

0.279

Low

1211651

FBP1L
Formin-binding protein 1-like

1

0

High-throughput

0.249

Low

914965

THOP1
Thimet oligopeptidase

1

0

High-throughput

0.232

Low

1429598

CWC22
Pre-mRNA-splicing factor CWC22 homolog

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025