HitPredict

Interactor 1: PLCG1 (P19174)
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 (EC 3.1.4.11) (PLC-148) (Phosphoinositide phospholipase C-gamma-1) (Phospholipase C-II) (PLC-II) (Phospholipase C-gamma-1) (PLC-gamma-1)
Gene: PLCG1

Interactor 2: LZTS2 (Q9BRK4)
Leucine zipper putative tumor suppressor 2 (hLZTS2) (Protein LAPSER1)
Gene: LZTS2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0005886 - plasma membrane
Homologous interactions	3

Homologous interactions

Color coding for hit scores

	1 1290 Hs			1 669
+	Hs
		1117594 PLCH1_HUMAN (847-1284): 8.88e-86: 310: 27.09		LZTS2_HUMAN (1-669): 6.28e-56: 203: 100.00
+	Hs
		846021 PLCD1_HUMAN (734-1213): 1.5e-93: 320: 23.73		PLEC_HUMAN (327-659): 1.61e-09: 63.5: 20.77
+	Mm
		719322 PTN11_MOUSE (546-769): 4.4e-68: 243: 26.86		ITSN1_MOUSE (3-554): 8.1e-12: 70.8: 12.08