HitPredict

Interactor 1: TAU (P19332)
Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau)
Gene: Mapt

Interactor 2: AP2B1 (P62944)
AP-2 complex subunit beta (AP105B) (Adaptor protein complex AP-2 subunit beta) (Adaptor-related protein complex 2 subunit beta) (Beta-2-adaptin) (Beta-adaptin) (Clathrin assembly protein complex 2 beta large chain) (Plasma membrane adaptor HA2/AP2 adaptin beta subunit)
Gene: AP2B1

Species: Rattus norvegicus

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	32357304
Identification Methods	cross-linking study
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0044877 - protein-containing complex binding
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 752 Rn			1 937
+	Rn
		94193 F1LST4_RAT (1-751): 5.68e-95: 314: 99.87		AP2B1_RAT (1-937): 0: 926: 100.00
+	Mm
		498136 TAU_MOUSE (1-752): 1.92e-82: 279: 89.52		AP2B1_MOUSE (1-937): 0: 926: 99.89
+	Hs
		496790 TAU_HUMAN (1-752): 2.05e-72: 253: 71.86		AP2B1_HUMAN (1-937): 0: 926: 100.00
+	Hs
		496926 TAU_HUMAN (1-752): 2.05e-72: 253: 71.86		AP1B1_HUMAN (1-937): 0: 888: 82.72
+	Hs
		926047 MAGL2_HUMAN (19-689): 6.16e-10: 65.1: 8.17		AP2B1_HUMAN (1-937): 0: 926: 100.00
+	Hs
		203219 SYNJ1_HUMAN (395-731): 7.71e-09: 61.6: 13.27		AP2B1_HUMAN (1-937): 0: 926: 100.00
+	Hs
		1014106 CABIN_HUMAN (103-561): 3.85e-12: 72.2: 12.26		AP1B1_HUMAN (1-937): 0: 888: 82.72
+	Hs
		203223 SYNJ1_HUMAN (395-731): 7.71e-09: 61.6: 13.27		AP1B1_HUMAN (1-937): 0: 888: 82.72
+	Mm
		497920 TAU_MOUSE (1-752): 1.92e-82: 279: 89.52		AP2A1_MOUSE (11-932): 0: 633: 17.04
+	Rn
		577190 TAU_RAT (1-752): 2.4e-95: 314: 100.00		AP2A2_RAT (11-932): 0: 595: 16.50
+	Rn
		94239 F1LST4_RAT (1-751): 5.68e-95: 314: 99.87		Q66HM2_RAT (11-932): 0: 590: 16.38
+	Hs
		321471 TAU_HUMAN (1-752): 2.05e-72: 253: 71.86		AP2A1_HUMAN (11-932): 0: 634: 16.97
+	Hs
		302095 TAU_HUMAN (1-752): 2.05e-72: 253: 71.86		AP2A2_HUMAN (11-933): 0: 600: 16.99
+	Hs
		496624 TAU_HUMAN (1-752): 2.05e-72: 253: 71.86		COPB_HUMAN (8-927): 0: 561: 12.47
+	Mm
		498147 TAU_MOUSE (1-752): 1.92e-82: 279: 89.52		AP3B2_MOUSE (16-594): 1.24e-173: 535: 28.71
+	Hs
		496962 TAU_HUMAN (1-752): 2.05e-72: 253: 71.86		AP3B2_HUMAN (16-594): 2.55e-174: 537: 28.71
+	Hs
		212589 TAU_HUMAN (1-752): 2.05e-72: 253: 71.86		AP1G1_HUMAN (11-808): 1.03e-173: 527: 17.57
+	Hs
		203194 SYNJ1_HUMAN (395-731): 7.71e-09: 61.6: 13.27		AP2A1_HUMAN (11-932): 0: 634: 16.97
+	Rn
		1144064 SYNJ1_RAT (328-740): 1.95e-12: 73.2: 12.80		Q66HM2_RAT (11-932): 0: 590: 16.38