HitPredict

Interactor 1: NUCL (P19338)
Nucleolin (Protein C23)
Gene: NCL

Interactor 2: DDX41 (Q9UJV9)
Probable ATP-dependent RNA helicase DDX41 (EC 3.6.4.13) (DEAD box protein 41) (DEAD box protein abstrakt homolog)
Gene: DDX41

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.54	0.60	0.571

Property	Details
Experiments	27049334, 25920683
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005681 - spliceosomal complex GO:0016020 - membrane
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 710 Hs			1 622
+	Hs
		571302 NUCL_HUMAN (1-650): 8.84e-98: 318: 100.00		DDX5_HUMAN (88-617): 1.42e-145: 437: 30.80
+	Hs
		133876 NUCL_HUMAN (1-650): 8.84e-98: 318: 100.00		DDX3X_HUMAN (19-592): 1.62e-139: 423: 29.70
+	Hs
		133858 PABP1_HUMAN (222-482): 4.4e-43: 167: 15.55		DDX3X_HUMAN (19-592): 1.62e-139: 423: 29.70
+	Hs
		134018 PABP4_HUMAN (222-488): 1.86e-42: 165: 14.88		DDX3X_HUMAN (19-592): 1.62e-139: 423: 29.70
+	Sc
		624051 PUB1_YEAST (475-648): 4.1e-16: 83.6: 28.89		DBP2_YEAST (71-563): 6.45e-141: 422: 35.14
+	Sc
		624213 PUB1_YEAST (475-648): 4.1e-16: 83.6: 28.89		DBP1_YEAST (25-570): 3.7e-137: 415: 29.75
+	Sc
		376580 PABP_YEAST (181-555): 3.61e-53: 194: 17.47		DED1_YEAST (173-589): 1.72e-89: 291: 38.93
+	Sc
		415924 PUB1_YEAST (475-648): 4.1e-16: 83.6: 28.89		DED1_YEAST (173-589): 1.72e-89: 291: 38.93