HitPredict

Interactor 1: SL9A1 (P19634)
Sodium/hydrogen exchanger 1 (APNH) (Na(+)/H(+) antiporter, amiloride-sensitive) (Na(+)/H(+) exchanger 1) (NHE-1) (Solute carrier family 9 member 1)
Gene: SLC9A1

Interactor 2: RAC3 (P60763)
Ras-related C3 botulinum toxin substrate 3 (EC 3.6.5.2) (p21-Rac3)
Gene: RAC3

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0030027 - lamellipodium GO:0048306 - calcium-dependent protein binding GO:0048471 - perinuclear region of cytoplasm GO:0070062 - extracellular exosome
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 815 Hs			1 192
+	Hs
		586027 SL9A1_HUMAN (1-815): 0: 823: 100.00		RAC1_HUMAN (1-192): 1.92e-84: 249: 92.71
+	Hs
		545203 SL9A1_HUMAN (1-815): 0: 823: 100.00		RAC2_HUMAN (1-192): 6.96e-81: 240: 88.54
+	Hs
		586069 SL9A1_HUMAN (1-815): 0: 823: 100.00		RHOJ_HUMAN (2-190): 2.64e-80: 239: 60.32
+	Hs
		586031 SL9A1_HUMAN (1-815): 0: 823: 100.00		RHOG_HUMAN (1-192): 2.62e-78: 233: 69.79
+	Hs
		586022 SL9A1_HUMAN (1-815): 0: 823: 100.00		CDC42_HUMAN (1-192): 3.66e-77: 230: 68.75
+	Hs
		586024 SL9A1_HUMAN (1-815): 0: 823: 100.00		RHOA_HUMAN (5-192): 2.22e-76: 228: 55.32
+	Hs
		436155 SL9A1_HUMAN (1-815): 0: 823: 100.00		RHOC_HUMAN (5-192): 2.99e-74: 223: 54.79
+	Hs
		564409 SL9A1_HUMAN (1-815): 0: 823: 100.00		RHOQ_HUMAN (4-189): 1.4e-73: 222: 63.49
+	Hs
		892519 SL9A6_HUMAN (155-564): 2.62e-105: 341: 28.33		RAC3_HUMAN (1-192): 5.54e-79: 235: 100.00