Protein: SWR1
Helicase SWR1 (EC 3.6.4.12) (Swi2/Snf2-related 1)

Gene: SWR1
Organism: Saccharomyces cerevisiae S288C
Interactions: 91
UniProt ID: Q05471

Gene Ontology (top 5):
GO:0000725 - recombinational repair
GO:0000785 - chromatin
GO:0000812 - Swr1 complex
GO:0003677 - DNA binding
GO:0004386 - helicase activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1044460

RUVB1
RuvB-like protein 1

21

20

Small-scale

0.988

High

1051142

RUVB2
RuvB-like protein 2

21

20

Small-scale

0.988

High

1010211

ARP4
Actin-related protein 4

22

20

Small-scale

0.988

High

918174

SWC4
SWR1-complex protein 4

20

7

Small-scale

0.987

High

1042548

VPS72
Vacuolar protein sorting-associated protein 72

20

4

Small-scale

0.987

High

948656

ACT
Actin

18

20

Small-scale

0.985

High

1051143

ARP6
Actin-like protein ARP6

17

20

Small-scale

0.984

High

1051144

H2AZ
Histone H2A.Z

11

20

Small-scale

0.975

High

381266

H2B1
Histone H2B.1

6

20

Small-scale

0.933

High

419505

H2A1
Histone H2A.1

5

20

Small-scale

0.915

High

381637

H2B2
Histone H2B.2

4

20

Small-scale

0.878

High

382345

H4
Histone H4

3

14

Small-scale

0.827

High

419876

H2A2
Histone H2A.2

2

20

Small-scale

0.768

High

924901

AF9
Protein AF-9 homolog

21

8

Small-scale

0.765

High

798129

SWC5
SWR1-complex protein 5

19

3

Small-scale

0.763

High

777119

BDF1
Bromodomain-containing factor 1

16

20

Small-scale

0.759

High

963718

H3
Histone H3

2

20

Small-scale

0.755

High

820304

IES2
Ino eighty subunit 2

2

2

Small-scale

0.754

High

1042799

VPS71
Vacuolar protein sorting-associated protein 71

20

0

Small-scale

0.732

High

725983

SWC3
SWR1-complex protein 3

18

0

Small-scale

0.730

High

1051136

SWC7
SWR1-complex protein 7

15

0

Small-scale

0.727

High

925244

ARP5
Actin-related protein 5

1

20

Small-scale

0.618

High

1051141

ARP8
Actin-like protein ARP8

1

20

Small-scale

0.618

High

743140

STH1
Nuclear protein STH1/NPS1

1

15

High-throughput

0.575

High

744346

CHD1
Chromo domain-containing protein 1

1

18

High-throughput

0.575

High

794222

ISW1
ISWI chromatin-remodeling complex ATPase ISW1

1

16

High-throughput

0.575

High

1050593

ARP9
Actin-like protein ARP9

1

20

High-throughput

0.575

High

1051133

SWR1
Helicase SWR1

1

14

High-throughput

0.575

High

850577

RSC8
Chromatin structure-remodeling complex protein RSC8

2

20

High-throughput

0.571

High

802074

ARP1
Centractin

1

20

Small-scale

0.553

High

682941

MSH2
DNA mismatch repair protein MSH2

1

2

High-throughput

0.541

High

779837

SIS2
Phosphopantothenoylcysteine decarboxylase subunit SIS2

1

1

High-throughput

0.515

High

945349

LSM3
LSM complex subunit LSM3

1

4

High-throughput

0.515

High

364739

CDK1
Cyclin-dependent kinase 1

1

1

High-throughput

0.479

High

576007

CYPH
Peptidyl-prolyl cis-trans isomerase

1

5

High-throughput

0.479

High

586021

CSK21
Casein kinase II subunit alpha

1

8

High-throughput

0.479

High

623014

CSK22
Casein kinase II subunit alpha'

1

11

High-throughput

0.479

High

708183

TF2B
Transcription initiation factor IIB

1

3

High-throughput

0.479

High

739201

PRP19
Pre-mRNA-processing factor 19

1

10

Small-scale

0.479

High

739774

SPT16
FACT complex subunit SPT16

1

2

High-throughput

0.479

High

743287

PP12
Serine/threonine-protein phosphatase PP1-2

1

4

Small-scale

0.479

High

743847

IES6
Chromatin-remodeling complex subunit IES6

1

3

Small-scale

0.479

High

745876

GSP1
GTP-binding nuclear protein GSP1/CNR1

1

8

High-throughput

0.479

High

763375

TAF14
Transcription initiation factor TFIID subunit 14

1

8

Small-scale

0.479

High

764005

SPT10
Protein SPT10

1

3

High-throughput

0.479

High

817712

IES5
Ino eighty subunit 5

1

1

Small-scale

0.479

High

818513

SCC4
MAU2 chromatid cohesion factor homolog

1

3

Small-scale

0.479

High

823040

ATAD2
ATPase histone chaperone YTA7

1

6

High-throughput

0.479

High

826835

DSN1
Kinetochore-associated protein DSN1

1

3

High-throughput

0.479

High

849895

IES1
Ino eighty subunit 1

1

1

Small-scale

0.479

High

1042811

NHP10
Non-histone protein 10

1

20

Small-scale

0.479

High

1051138

IES4
Ino eighty subunit 4

1

1

Small-scale

0.479

High

1051140

IES3
Ino eighty subunit 3

1

2

Small-scale

0.479

High

633272

CKS1
Cyclin-dependent kinases regulatory subunit

1

0

Small-scale

0.458

High

910786

SKP1
Suppressor of kinetochore protein 1

1

0

High-throughput

0.458

High

448405

RAD1
DNA repair protein RAD1

1

1

High-throughput

0.457

High

393327

HSP82
ATP-dependent molecular chaperone HSP82

1

8

High-throughput

0.445

High

510819

HSP77
Import motor subunit, mitochondrial

1

13

High-throughput

0.445

High

525149

HSP71
Heat shock protein SSA1

1

14

High-throughput

0.445

High

527676

HSP72
Heat shock protein SSA2

1

14

High-throughput

0.445

High

546270

SSB1
Ribosome-associated molecular chaperone SSB1

1

12

High-throughput

0.445

High

580066

HSC82
ATP-dependent molecular chaperone HSC82

1

8

High-throughput

0.445

High

676347

MAS5
Mitochondrial protein import protein MAS5

1

4

High-throughput

0.445

High

678345

RSC6
Chromatin structure-remodeling complex protein RSC6

1

20

High-throughput

0.445

High

713038

MCM2
DNA replication licensing factor MCM2

1

5

High-throughput

0.445

High

742392

HSP7F
Heat shock protein homolog SSE1

1

20

High-throughput

0.445

High

752729

HSP78
Heat shock protein 78, mitochondrial

1

4

High-throughput

0.445

High

811494

XDJ1
DnaJ protein homolog XDJ1

1

4

High-throughput

0.445

High

816406

HSP7E
Heat shock protein SSC3, mitochondrial

1

13

High-throughput

0.445

High

823653

TCPE
T-complex protein 1 subunit epsilon

1

1

High-throughput

0.445

High

826488

DJP1
DnaJ-like protein 1

1

3

High-throughput

0.445

High

921166

H1
Histone H1

1

1

High-throughput

0.445

High

1026830

CDC14
Tyrosine-protein phosphatase CDC14

1

2

High-throughput

0.445

High

1035329

RSC4
Chromatin structure-remodeling complex subunit RSC4

1

20

High-throughput

0.445

High

1043973

TAF12
SAGA complex/transcription factor TFIID complex subunit TAF12

1

5

High-throughput

0.445

High

1051134

RSC2
Chromatin structure-remodeling complex subunit RSC2

1

20

High-throughput

0.445

High

1051137

RSC58
Chromatin structure-remodeling complex protein RSC58

1

1

High-throughput

0.445

High

807785

CSK2C
Casein kinase II subunit beta'

1

4

High-throughput

0.437

High

851016

CSK2B
Casein kinase II subunit beta

1

4

High-throughput

0.437

High

794296

CHK1
Serine/threonine-protein kinase CHK1

1

0

High-throughput

0.426

High

803777

PIH1
Protein interacting with Hsp90 1

1

0

High-throughput

0.426

High

844445

TCPH
T-complex protein 1 subunit eta

1

0

High-throughput

0.426

High

912445

PFD6
Prefoldin subunit 6

1

0

High-throughput

0.426

High

1041000

RSC9
Chromatin structure-remodeling complex subunit RSC9

1

0

High-throughput

0.426

High

1051135

RSC3
Chromatin structure-remodeling complex protein RSC3

1

0

High-throughput

0.426

High

577213

SEC63
Protein translocation protein SEC63

1

4

High-throughput

0.407

High

1051139

HSP42
Heat shock protein 42

1

1

High-throughput

0.407

High

918689

PIL1
Sphingolipid long chain base-responsive protein PIL1

1

0

High-throughput

0.269

Low

863734

PFD1
Prefoldin subunit 1

1

0

High-throughput

0.232

Low

864330

NET1
Nucleolar protein NET1

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025