HitPredict

Interactor 1: PRP6 (P19735)
Pre-mRNA-splicing factor 6
Gene: PRP6

Interactor 2: EF2 (P32324)
Elongation factor 2 (EF-2) (EC 3.6.5.-) (Eukaryotic elongation factor 2) (eEF2) (Ribosomal translocase) (Translation elongation factor 2)
Gene: EFT1

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.50	0.457

Property	Details
Experiments	11805837
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 899 Sc			1 842
+	Hs
		300149 PRP6_HUMAN (2-895): 6.07e-177: 538: 25.44		U5S1_HUMAN (1-840): 0: 813: 36.35
+	Sp
		292954 PRP1_SCHPO (4-897): 2.68e-151: 470: 25.87		SN114_SCHPO (2-841): 0: 746: 34.30
+	Sc
		586391 PRP6_YEAST (1-899): 0: 558: 100.00		SN114_YEAST (2-839): 0: 580: 25.06
+	Sc
		687481 RRP5_YEAST (657-864): 1.15e-10: 68: 15.35		EF2_YEAST (1-842): 0: 957: 100.00
+	Hs
		174901 OGT1_HUMAN (141-597): 4e-41: 165: 11.74		U5S1_HUMAN (1-840): 0: 813: 36.35
+	Dm
		571949 CRN_DROME (314-890): 4.87e-38: 154: 12.50		Q9VAX8_DROME (2-840): 0: 808: 35.35
+	Dm
		54170 SYF1_DROME (208-718): 2.8e-17: 88.9: 10.46		Q9VAX8_DROME (2-840): 0: 808: 35.35
+	Hs
		1064694 CRNL1_HUMAN (687-884): 2.75e-15: 82.7: 13.93		U5S1_HUMAN (1-840): 0: 813: 36.35
+	Hs
		1064742 SYF1_HUMAN (207-515): 3.46e-09: 62.7: 12.98		U5S1_HUMAN (1-840): 0: 813: 36.35
+	Sp
		292943 CLF1_SCHPO (687-895): 3.18e-16: 85.4: 12.15		SN114_SCHPO (2-841): 0: 746: 34.30
+	Sp
		292962 SYF1_SCHPO (190-709): 7.6e-16: 84.3: 8.79		SN114_SCHPO (2-841): 0: 746: 34.30
+	Sc
		731786 CLF1_YEAST (222-440): 1.03e-13: 77.3: 14.41		SN114_YEAST (2-839): 0: 580: 25.06
+	Sc
		731769 SYF1_YEAST (229-761): 2.59e-10: 66.5: 11.46		SN114_YEAST (2-839): 0: 580: 25.06