Interactor 1: NFKB1 (P19838)
Nuclear factor NF-kappa-B p105 subunit (DNA-binding factor KBF1) (EBP-1) (Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1) [Cleaved into: Nuclear factor NF-kappa-B p50 subunit]
Gene: NFKB1
Interactor 2: NFKB1 (P19838)
Nuclear factor NF-kappa-B p105 subunit (DNA-binding factor KBF1) (EBP-1) (Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1) [Cleaved into: Nuclear factor NF-kappa-B p50 subunit]
Gene: NFKB1
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
Method score | Annotation score | Interaction score |
---|---|---|
0.97 | 1.00 | 0.987 |
The method score is based on:
Property | Details |
---|---|
Experiments | 12414801, 14743216, 8428580, 26264872, 11880271, 14645533, 21988832, 1508666, 15043934, 8887676, 9722548, 9315679, 9405619, 15722553, 18321863, 12115600, 12388374, 12218129, 12832462, 25609649 and 1 others
more... |
Identification Methods | pull down, affinity chromatography technology, two hybrid, electrophoretic mobility supershift assay, electrophoretic mobility shift assay, anti tag coimmunoprecipitation, cosedimentation, tandem affinity purification |
Interaction Type | direct interaction, physical association, association |
The annotation score is based on:
Property | Details |
---|---|
Interacting Pfam domains | Ank~Ank, Ank~Ank_2, Ank~RHD_dimer, Ank_2~Ank_2, Ank_2~RHD_dimer, Death~Death, RHD_dimer~RHD_dimer, RHD_DNA_bind~RHD_dimer, RHD_DNA_bind~RHD_DNA_bind |
Common GO terms | GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0000785 - chromatin GO:0000976 - transcription cis-regulatory region binding GO:0000977 - RNA polymerase II transcription regulatory region sequence-specific DNA binding GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding and 57 others more... |
Homologous interactions | 18 |
Homologous interactions
Color coding for hit scores
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Last updated: 15 Jul 2024