Protein: DCNL5
DCN1-like protein 5 (DCNL5) (DCUN1 domain-containing protein 5) (Defective in cullin neddylation protein 1-like protein 5) (Squamous cell carcinoma-related oncogene 5)

Gene: DCNL5, DCUN1D5
Organism: Homo sapiens
Interactions: 71
UniProt ID: Q9BTE7

Gene Ontology (top 5):
GO:0000151 - ubiquitin ligase complex
GO:0001558 - regulation of cell growth
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0005819 - spindle

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1042423

CUL3
Cullin-3

3

20

Small-scale

0.875

High

1041180

CUL1
Cullin-1

3

20

Small-scale

0.847

High

1274037

CUL5
Cullin-5

3

20

Small-scale

0.847

High

1041455

CUL2
Cullin-2

4

20

Small-scale

0.796

High

1043197

CUL4A
Cullin-4A

2

20

Small-scale

0.789

High

1043549

CUL4B
Cullin-4B

2

20

Small-scale

0.789

High

896205

UBC12
NEDD8-conjugating enzyme Ubc12

4

10

Small-scale

0.686

High

444776

GNAI3
Guanine nucleotide-binding protein G(i) subunit alpha-3

3

0

High-throughput

0.638

High

1082625

MK14
Mitogen-activated protein kinase 14

3

0

High-throughput

0.638

High

1202086

CAND1
Cullin-associated NEDD8-dissociated protein 1

2

4

Small-scale

0.624

High

1123314

PKHG4
Puratrophin-1

2

1

High-throughput

0.606

High

1233327

PNKD
Probable hydrolase PNKD

2

0

High-throughput

0.585

High

921411

RBX1
E3 ubiquitin-protein ligase RBX1

2

9

Small-scale

0.584

High

245916

HUS1
Checkpoint protein HUS1

2

0

High-throughput

0.580

High

1312190

PICK1
PRKCA-binding protein

2

0

High-throughput

0.580

High

1252442

LNX1
E3 ubiquitin-protein ligase LNX

1

3

High-throughput

0.573

High

885183

FOXL2
Forkhead box protein L2

1

1

High-throughput

0.536

High

1021346

FOXL1
Forkhead box protein L1

1

1

High-throughput

0.536

High

1299459

ZN363
RING finger and CHY zinc finger domain-containing protein 1

1

0

High-throughput

0.518

High

146644

SOCS2
Suppressor of cytokine signaling 2

1

3

High-throughput

0.515

High

147556

SOCS6
Suppressor of cytokine signaling 6

1

3

High-throughput

0.515

High

283660

JTB
Protein JTB

1

0

High-throughput

0.513

High

958515

CYC
Cytochrome c

1

0

High-throughput

0.513

High

1075248

TEAD2
Transcriptional enhancer factor TEF-4

1

0

High-throughput

0.513

High

1169184

RN111
E3 ubiquitin-protein ligase Arkadia

1

0

High-throughput

0.513

High

1218951

HSC20
Iron-sulfur cluster co-chaperone protein HscB

1

0

High-throughput

0.513

High

1284786

EFMT3
EEF1A lysine methyltransferase 3

1

0

High-throughput

0.513

High

1312188

GSX1
GS homeobox 1

1

0

High-throughput

0.513

High

1281715

UBE2F
NEDD8-conjugating enzyme UBE2F

1

10

Small-scale

0.501

High

760276

RL3
Large ribosomal subunit protein uL3

1

0

High-throughput

0.493

High

999660

AHNK
Neuroblast differentiation-associated protein AHNAK

1

0

High-throughput

0.493

High

1271950

KLK6
Kallikrein-6

1

0

High-throughput

0.493

High

196860

CYB5B
Cytochrome b5 type B

1

1

High-throughput

0.489

High

167607

IKKA
Inhibitor of nuclear factor kappa-B kinase subunit alpha

1

0

Small-scale

0.480

High

228536

PRKN
E3 ubiquitin-protein ligase parkin

1

4

High-throughput

0.479

High

553585

RFA2
Replication protein A 32 kDa subunit

1

2

High-throughput

0.479

High

631566

BRD2
Bromodomain-containing protein 2

1

2

High-throughput

0.479

High

652111

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

2

High-throughput

0.479

High

909044

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

1

High-throughput

0.479

High

935187

H31
Histone H3.1

1

3

High-throughput

0.479

High

952596

H33
Histone H3.3

1

3

High-throughput

0.479

High

1082363

DDB1
DNA damage-binding protein 1

1

1

Small-scale

0.479

High

1312193

HECW2
E3 ubiquitin-protein ligase HECW2

1

1

High-throughput

0.479

High

1312194

RBX2
RING-box protein 2

1

9

Small-scale

0.479

High

573881

PTN1
Tyrosine-protein phosphatase non-receptor type 1

1

0

High-throughput

0.458

High

867249

TCP4
Activated RNA polymerase II transcriptional coactivator p15

1

0

High-throughput

0.458

High

1265892

DDB2
DNA damage-binding protein 2

1

0

High-throughput

0.458

High

1287354

OPTN
Optineurin

1

0

High-throughput

0.458

High

721306

RFA3
Replication protein A 14 kDa subunit

1

2

High-throughput

0.437

High

1163827

RICTR
Rapamycin-insensitive companion of mTOR

1

1

High-throughput

0.437

High

1312189

PACC1
Proton-activated chloride channel

2

0

High-throughput

0.328

High

310342

LYPD3
Ly6/PLAUR domain-containing protein 3

2

0

High-throughput

0.318

High

1230105

F177A
Protein FAM177A1

2

0

High-throughput

0.318

High

57971

TM213
Transmembrane protein 213

1

0

High-throughput

0.279

Low

351187

TGFA
Protransforming growth factor alpha [Cleaved into: Transforming growth factor alpha

1

0

High-throughput

0.279

Low

362278

GLPA
Glycophorin-A

1

0

High-throughput

0.279

Low

702287

CD70
CD70 antigen

1

0

High-throughput

0.279

Low

813719

CAPZB
F-actin-capping protein subunit beta

1

0

High-throughput

0.279

Low

1031066

GPR17
Uracil nucleotide/cysteinyl leukotriene receptor

1

0

High-throughput

0.279

Low

1059502

FXYD3
FXYD domain-containing ion transport regulator 3

1

0

High-throughput

0.279

Low

1110430

KR197
Keratin-associated protein 19-7

1

0

High-throughput

0.279

Low

1166487

ELAP1
Endosome/lysosome-associated apoptosis and autophagy regulator 1

1

0

High-throughput

0.279

Low

1285608

I27L1
Interferon alpha-inducible protein 27-like protein 1

1

0

High-throughput

0.279

Low

1296200

COX42
Cytochrome c oxidase subunit 4 isoform 2, mitochondrial

1

0

High-throughput

0.279

Low

1312191

FGOP2
FGFR1 oncogene partner 2

1

0

High-throughput

0.279

Low

1312192

ORML1
ORM1-like protein 1

1

0

High-throughput

0.279

Low

1312195

CC018
Uncharacterized protein C3orf18

1

0

High-throughput

0.279

Low

1312196

FIS1
Mitochondrial fission 1 protein

1

0

High-throughput

0.279

Low

1051662

DYHC1
Cytoplasmic dynein 1 heavy chain 1

1

0

High-throughput

0.268

Low

832931

ACADV
Very long-chain specific acyl-CoA dehydrogenase, mitochondrial

1

0

Small-scale

0.249

Low

1146165

DCA15
DDB1- and CUL4-associated factor 15

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024