Interactor 1: NFKB1 (P19838)
Nuclear factor NF-kappa-B p105 subunit (DNA-binding factor KBF1) (EBP-1) (Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1) [Cleaved into: Nuclear factor NF-kappa-B p50 subunit]
Gene: NFKB1

Interactor 2: TNIP2 (Q8NFZ5)
TNFAIP3-interacting protein 2 (A20-binding inhibitor of NF-kappa-B activation 2) (ABIN-2) (Fetal liver LKB1-interacting protein)
Gene: TNIP2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.94 0.60 0.753

The method score is based on:

Property Details
Experiments 29084252, 27609421, 15169888, 25609649, 14743216, 35140242, 21988832
Identification Methods protein complementation assay, affinity chromatography technology, pull down, fluorescent resonance energy transfer, proximity labelling technology, two hybrid, tandem affinity purification, anti tag coimmunoprecipitation, anti bait coimmunoprecipitation
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005654 - nucleoplasm
GO:0005829 - cytosol
GO:0006357 - regulation of transcription by RNA polymerase II
GO:0006915 - apoptotic process
GO:0006954 - inflammatory response
and 2 others

more...

Homologous interactions 5

Homologous interactions

Color coding for hit scores

1 968
Hs

1 429
+ Mm
+ Hs
+ Hs
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024