HitPredict

Interactor 1: NRG (P20241)
Neuroglian
Gene: NRG

Interactor 2: Q9VHK4 (Q9VHK4)
Polychaetoid, isoform B
Gene: pyd

Species: Drosophila melanogaster

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	1.00	0.647

Property	Details
Experiments	21389050
Identification Methods	far western blotting
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	PDZ~fn3
Common GO terms	GO:0005886 - plasma membrane GO:0030424 - axon GO:0050839 - cell adhesion molecule binding GO:0098609 - cell-cell adhesion
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 1302 Dm			1 1371
+	Dm
		333139 SDK_DROME (718-1296): 8.53e-12: 72.5: 8.78		Q9VHK4_DROME (1-1371): 0: 1114: 100.00
+	Mm
		1143386 NRCAM_MOUSE (6-1250): 0: 649: 29.25		DLG4_MOUSE (6-305): 2.58e-24: 112: 14.15
+	Mm
		1195001 NRCAM_MOUSE (6-1250): 0: 649: 29.25		DLG1_MOUSE (6-118): 9.49e-15: 81.8: 30.44
+	Mm
		524114 CNTN1_MOUSE (221-1180): 1.15e-89: 315: 14.27		DLG4_MOUSE (6-305): 2.58e-24: 112: 14.15
+	Mm
		936319 DCC_MOUSE (420-1131): 1.27e-75: 278: 16.91		DLG4_MOUSE (6-305): 2.58e-24: 112: 14.15
+	Hs
		234509 DSCAM_HUMAN (636-1299): 3.72e-15: 83.3: 8.77		PTN13_HUMAN (15-501): 2.39e-36: 152: 14.66
+	Mm
		1143349 SDK2_MOUSE (697-1296): 7.18e-19: 95.6: 8.56		DLG4_MOUSE (6-305): 2.58e-24: 112: 14.15
+	Rn
		88572 D3ZDA6_RAT (839-1296): 3.21e-15: 83.7: 9.73		DLG4_RAT (6-305): 3.74e-24: 111: 14.89
+	Hs
		234499 DSCAM_HUMAN (636-1299): 3.72e-15: 83.3: 8.77		DLG4_HUMAN (6-305): 4.61e-24: 111: 14.15
+	Rn
		88575 D3ZDA6_RAT (839-1296): 3.21e-15: 83.7: 9.73		DLG2_RAT (329-487): 6.34e-16: 85.7: 17.26
+	Hs
		234511 DSCAM_HUMAN (636-1299): 3.72e-15: 83.3: 8.77		DLG1_HUMAN (6-118): 1.41e-15: 84.5: 31.30
+	Hs
		234522 DSCAM_HUMAN (636-1299): 3.72e-15: 83.3: 8.77		DLG2_HUMAN (329-487): 1.33e-15: 84.5: 17.26
+	Rn
		88574 D3ZDA6_RAT (839-1296): 3.21e-15: 83.7: 9.73		DLG3_RAT (295-655): 2.57e-11: 70.6: 13.28