HitPredict

Interactor 1: TNR1B (P20333)
Tumor necrosis factor receptor superfamily member 1B (Tumor necrosis factor receptor 2) (TNF-R2) (Tumor necrosis factor receptor type II) (TNF-RII) (TNFR-II) (p75) (p80 TNF-alpha receptor) (CD antigen CD120b) (Etanercept) [Cleaved into: Tumor necrosis factor receptor superfamily member 1b, membrane form; Tumor necrosis factor-binding protein 2 (TBP-2) (TBPII)]
Gene: TNFRSF1B

Interactor 2: PKN1 (Q16512)
Serine/threonine-protein kinase N1 (EC 2.7.11.13) (Protease-activated kinase 1) (PAK-1) (Protein kinase C-like 1) (Protein kinase C-like PKN) (Protein kinase PKN-alpha) (Protein-kinase C-related kinase 1) (Serine-threonine protein kinase N)
Gene: PKN1

Species: Homo sapiens

Source: innatedb

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.55	0.50	0.528

Property	Details
Experiments	18429822
Identification Methods	affinity chromatography technology, pull down, anti tag coimmunoprecipitation
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 461 Hs			1 942
+	Hs
		408551 TNR1A_HUMAN (32-256): 2.62e-36: 141: 22.36		KPCB_HUMAN (462-940): 3.02e-167: 505: 36.12
+	Hs
		584328 TNR1A_HUMAN (32-256): 2.62e-36: 141: 22.36		AKT1_HUMAN (587-941): 7.64e-153: 461: 43.06
+	Mm
		812910 TNR4_MOUSE (44-248): 4.51e-37: 138: 26.54		KPCT_MOUSE (535-941): 7.79e-149: 459: 42.23
+	Mm
		554864 TNR1A_MOUSE (32-256): 4.92e-32: 129: 20.24		KPCE_MOUSE (484-937): 2.92e-147: 456: 35.52
+	Hs
		632253 TNR6_HUMAN (44-320): 6.35e-39: 145: 15.77		KPCD_HUMAN (608-938): 7.48e-103: 337: 50.30
+	Hs
		584382 TNR1A_HUMAN (32-256): 2.62e-36: 141: 22.36		KPCD_HUMAN (608-938): 7.48e-103: 337: 50.30
+	Mm
		626850 TNR1A_MOUSE (32-256): 4.92e-32: 129: 20.24		KPCD_MOUSE (611-938): 1.68e-102: 336: 49.54