HitPredict

Interactor 1: RAB3B (P20337)
Ras-related protein Rab-3B
Gene: RAB3B

Interactor 2: MSS4 (P47224)
Guanine nucleotide exchange factor MSS4 (Rab-interacting factor)
Gene: RABIF

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.73	0.80	0.768

Property	Details
Experiments	32296183, 33961781, unassigned1304
Identification Methods	two hybrid, affinity chromatography technology, two hybrid array, two hybrid prey pooling approach, validated two hybrid, anti tag coimmunoprecipitation
Interaction Type	direct interaction, physical association, association

Property	Details
Interacting Pfam domains	Mss4~Ras
Common GO terms	-
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 219 Hs			1 123
+	Hs
		812735 RAB8A_HUMAN (15-219): 2.07e-91: 268: 46.83		MSS4_HUMAN (1-123): 1.15e-71: 211: 100.00
+	Hs
		812737 RAB1A_HUMAN (12-219): 4.97e-88: 259: 42.31		MSS4_HUMAN (1-123): 1.15e-71: 211: 100.00
+	Mm
		918998 RAB1A_MOUSE (12-219): 4.97e-88: 259: 42.31		MSS4_MOUSE (1-123): 1.15e-71: 211: 93.50
+	Hs
		812757 RAB1B_HUMAN (15-219): 1.44e-86: 255: 42.44		MSS4_HUMAN (1-123): 1.15e-71: 211: 100.00
+	Hs
		320123 RAB3D_HUMAN (1-219): 1.01e-84: 252: 75.80		MSS4_HUMAN (1-123): 1.15e-71: 211: 100.00
+	Hs
		812752 RAB3C_HUMAN (1-219): 3.2e-84: 250: 80.82		MSS4_HUMAN (1-123): 1.15e-71: 211: 100.00
+	Hs
		591458 RAB3A_HUMAN (1-219): 1.23e-82: 246: 77.27		MSS4_HUMAN (1-123): 1.15e-71: 211: 100.00
+	Dm
		627448 RAB3_DROME (1-219): 6.46e-88: 260: 76.02		MSS4_DROME (13-123): 3.14e-52: 162: 39.29
+	Dm
		185502 O18332_DROME (12-218): 3.85e-84: 250: 41.06		MSS4_DROME (13-123): 3.14e-52: 162: 39.29
+	Hs
		812736 RAB10_HUMAN (15-186): 2.29e-63: 197: 52.91		MSS4_HUMAN (1-123): 1.15e-71: 211: 100.00
+	Hs
		812751 RAB8B_HUMAN (17-196): 7.4e-61: 191: 49.44		MSS4_HUMAN (1-123): 1.15e-71: 211: 100.00
+	Dm
		183445 O15971_DROME (15-188): 7.12e-65: 201: 53.45		MSS4_DROME (13-123): 3.14e-52: 162: 39.29