HitPredict

Interactor 1: RPAB3 (P20436)
DNA-directed RNA polymerases I, II, and III subunit RPABC3 (RNA polymerases I, II, and III subunit ABC3) (ABC14.4) (ABC14.5) (DNA-directed RNA polymerases I, II, and III 14.5 kDa polypeptide)
Gene: RPB8

Interactor 2: RPB11 (P38902)
DNA-directed RNA polymerase II subunit RPB11 (RNA polymerase II subunit B11) (B13.6) (DNA-directed RNA polymerase II 13.6 kDa polypeptide)
Gene: RPB11

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.87	1.00	0.933

The method score is based on:

Property	Details
Experiments	17937913, 25315781, 19394294, 21048197, 37968396, 23418395
Identification Methods	mass spectrometry studies of complexes, affinity chromatography technology
Interaction Type	direct interaction, physical association

The annotation score is based on:

Property	Details
Interacting Pfam domains	RNA_pol_L_2~RNA_pol_Rpb8
Common GO terms	GO:0001055 - RNA polymerase II activity GO:0001172 - RNA-templated transcription GO:0003677 - DNA binding GO:0005634 - nucleus GO:0005665 - RNA polymerase II, core complex and 3 others more... GO:0006366 - transcription by RNA polymerase II GO:0006367 - transcription initiation at RNA polymerase II promoter GO:0006368 - transcription elongation by RNA polymerase II
Homologous interactions	3

Homologous interactions

Color coding for hit scores

	1	146
Sc

1	120

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024