Interactor 1: NTF3 (P20783)
Neurotrophin-3 (NT-3) (HDNF) (Nerve growth factor 2) (NGF-2) (Neurotrophic factor)
Gene: NTF3

Interactor 2: NTRK3 (Q16288)
NT-3 growth factor receptor (EC 2.7.10.1) (GP145-TrkC) (Trk-C) (Neurotrophic tyrosine kinase receptor type 3) (TrkC tyrosine kinase)
Gene: NTRK3

Species: Homo sapiens

Source: dip

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.58 1.00 0.768

The method score is based on:

Property Details
Experiments 8621424, 10713102
Identification Methods pull down, biochemical
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains I-set~NGF
Common GO terms GO:0007169 - cell surface receptor protein tyrosine kinase signaling pathway
GO:0007399 - nervous system development
GO:0008284 - positive regulation of cell population proliferation
GO:0030335 - positive regulation of cell migration
GO:0030424 - axon
and 4 others

more...

Homologous interactions 9

Homologous interactions

Color coding for hit scores

1 257
Hs

1 839
+ Hs
+ Mm
+ Hs
+ Hs
+ Hs
+ Rn
+ Mm
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024