HitPredict

Interactor 1: RASA1 (P20936)
Ras GTPase-activating protein 1 (GAP) (GTPase-activating protein) (RasGAP) (Ras p21 protein activator) (p120GAP)
Gene: RASA1

Interactor 2: KHDR1 (Q07666)
KH domain-containing, RNA-binding, signal transduction-associated protein 1 (GAP-associated tyrosine phosphoprotein p62) (Src-associated in mitosis 68 kDa protein) (Sam68) (p21 Ras GTPase-activating protein-associated p62) (p68)
Gene: KHDRBS1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.91	0.60	0.739

Property	Details
Experiments	11604231, 9743338, 1545818, 1385407, 8419471, 8189062, 7537265
Identification Methods	affinity chromatography technology, pull down
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 1047 Hs			1 443
+	Mm
		93306 E9PYG6_MOUSE (1-1047): 0: 823: 95.03		KHDR1_MOUSE (1-443): 0: 514: 94.36
+	Hs
		991856 SYGP1_HUMAN (375-1030): 6.69e-106: 362: 19.45		KHDR1_HUMAN (1-443): 3.7e-177: 504: 100.00
+	Hs
		1139256 SYGP1_HUMAN (375-1030): 6.69e-106: 362: 19.45		KHDR2_HUMAN (99-443): 5.18e-130: 381: 60.62
+	Hs
		267538 SYGP1_HUMAN (375-1030): 6.69e-106: 362: 19.45		KHDR3_HUMAN (100-443): 1.37e-128: 377: 56.46
+	Hs
		267517 RASL3_HUMAN (496-1026): 1.2e-85: 300: 24.30		KHDR3_HUMAN (100-443): 1.37e-128: 377: 56.46
+	Hs
		924509 GRB2_HUMAN (181-317): 1.08e-10: 64.3: 30.71		KHDR1_HUMAN (1-443): 3.7e-177: 504: 100.00
+	Ce
		1229352 Q95XA9_CAEEL (143-1018): 2.07e-80: 283: 15.46		Q8MXD9_CAEEL (69-261): 3.71e-62: 205: 32.14