HitPredict

Interactor 1: NEBU (P20929)
Nebulin
Gene: NEB

Interactor 2: TITIN (Q8WZ42)
Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS-40.14)
Gene: TTN

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.70	0.60	0.649

Property	Details
Experiments	12482578, 16902413
Identification Methods	circular dichroism, nuclear magnetic resonance, classical fluorescence spectroscopy, two hybrid, isothermal titration calorimetry, filter binding
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0008307 - structural constituent of muscle GO:0030018 - Z disc GO:0051015 - actin filament binding GO:0070062 - extracellular exosome
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 8525 Hs			1 34350
+	Hs
		596200 NEBU_HUMAN (1-8525): 0: 8652: 100.00		MYOM2_HUMAN (2901-3346): 3.69e-09: 68.6: 21.30
+	Hs
		255770 SRC8_HUMAN (8096-8488): 8.57e-18: 93.5: 11.51		OBSL1_HUMAN (11917-12853): 4.17e-125: 446: 27.14
+	Hs
		363152 LASP1_HUMAN (5895-6038): 2.35e-10: 67.3: 18.06		FINC_HUMAN (26307-28070): 3.11e-129: 464: 16.42
+	Dm
		1181601 LASP1_DROME (7702-7839): 3.81e-09: 66.2: 20.86		Q7KQP6_DROME (3498-4065): 1.46e-24: 120: 15.88
+	Hs
		1052209 SRC8_HUMAN (8096-8488): 8.57e-18: 93.5: 11.51		MYLK_HUMAN (3583-3713): 7.51e-12: 77.7: 26.72
+	Dm
		54879 LASP1_DROME (7702-7839): 3.81e-09: 66.2: 20.86		A1ZA72_DROME (20624-20861): 3.94e-20: 105: 22.54
+	Dm
		1211900 LASP1_DROME (7702-7839): 3.81e-09: 66.2: 20.86		TITIN_DROME (31751-32109): 4.02e-19: 101: 20.17