Interactor 1: FLNA (P21333)
Filamin-A (FLN-A) (Actin-binding protein 280) (ABP-280) (Alpha-filamin) (Endothelial actin-binding protein) (Filamin-1) (Non-muscle filamin)
Gene: FLNA

Interactor 2: PSN2 (P49810)
Presenilin-2 (PS-2) (EC 3.4.23.-) (AD3LP) (AD5) (E5-1) (STM-2) [Cleaved into: Presenilin-2 NTF subunit; Presenilin-2 CTF subunit]
Gene: PSEN2

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.42 0.60 0.506

The method score is based on:

Property Details
Experiments 9437013
Identification Methods two hybrid, coimmunoprecipitation
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005886 - plasma membrane
GO:0016020 - membrane
GO:0030018 - Z disc
GO:0043066 - negative regulation of apoptotic process
GO:0043198 - dendritic shaft
and 1 others

more...

Homologous interactions 5

Homologous interactions

Color coding for hit scores

1 2647
Hs

1 448
+ Hs
+ Hs
+ Hs
+ Hs
+ Dm

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024