HitPredict

Interactor 1: A4FU91 (A4FU91)
Nucleoporin 58kDa L homeolog (Nupl1 protein)
Gene: nup58.L

Interactor 2: Q6PAY1 (Q6PAY1)
MGC68541 protein (Nucleoporin 54kDa S homeolog)
Gene: nup54.S

Species: Xenopus laevis

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.33	1.00	0.575

Property	Details
Experiments	22901806
Identification Methods	anti bait coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	Nucleoporin_FG2~Nup54, Nucleoporin_FG2~Nup54_C
Common GO terms	GO:0005829 - cytosol GO:0017056 - structural constituent of nuclear pore
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 593 Xl			1 502
+	Hs
		1188239 NUP58_HUMAN (1-593): 1.97e-95: 305: 69.85		NUP54_HUMAN (96-502): 6.02e-159: 462: 82.06
+	Rn
		936852 NUP58_RAT (1-593): 7.38e-93: 298: 71.26		NUP54_RAT (1-502): 4.98e-157: 458: 73.92
+	Xl
		111949 Q5EAX5_XENLA (1-593): 1.52e-74: 250: 78.55		K9ZTJ6_XENLA (1-502): 3.29e-157: 459: 92.15
+	Hs
		727310 NUP58_HUMAN (1-593): 1.97e-95: 305: 69.85		NU214_HUMAN (3-247): 7.98e-11: 66.9: 13.79
+	Sc
		822978 NU145_YEAST (1-326): 7.52e-36: 146: 17.40		NUP57_YEAST (2-479): 1.58e-66: 225: 18.46
+	Hs
		858043 NUP58_HUMAN (1-593): 1.97e-95: 305: 69.85		NUP98_HUMAN (87-300): 5.04e-09: 61.2: 12.61
+	Tt
		101859 NUP49_CHATD (4-367): 3.27e-24: 107: 15.17		NUP57_CHATD (185-491): 1.8e-80: 255: 17.13
+	Sc
		822988 NUP49_YEAST (2-382): 1.09e-32: 133: 18.30		NUP57_YEAST (2-479): 1.58e-66: 225: 18.46
+	Sc
		830664 NU145_YEAST (1-326): 7.52e-36: 146: 17.40		NU145_YEAST (4-362): 6.06e-51: 189: 11.49
+	Sc
		822976 NUP57_YEAST (2-229): 6.54e-19: 92.1: 22.04		NUP57_YEAST (2-479): 1.58e-66: 225: 18.46
+	Sc
		830671 NU145_YEAST (1-326): 7.52e-36: 146: 17.40		NUP49_YEAST (3-293): 1.39e-21: 99.3: 16.27
+	Sc
		969350 NUP49_YEAST (2-382): 1.09e-32: 133: 18.30		NUP49_YEAST (3-293): 1.39e-21: 99.3: 16.27
+	Ce
		1376904 Q9XWK3_CAEEL (39-570): 1.66e-42: 162: 18.07		Q9XWK3_CAEEL (5-196): 1.99e-09: 61.9: 17.73
+	Sc
		830674 NU145_YEAST (1-326): 7.52e-36: 146: 17.40		NU116_YEAST (2-254): 1.1e-12: 72.7: 15.81
+	Sc
		774360 NU145_YEAST (1-326): 7.52e-36: 146: 17.40		NU159_YEAST (6-274): 2.61e-11: 68.5: 9.76
+	Sc
		969353 NUP49_YEAST (2-382): 1.09e-32: 133: 18.30		NU116_YEAST (2-254): 1.1e-12: 72.7: 15.81
+	Sc
		774365 NUP49_YEAST (2-382): 1.09e-32: 133: 18.30		NU159_YEAST (6-274): 2.61e-11: 68.5: 9.76
+	Sc
		774358 NUP57_YEAST (2-229): 6.54e-19: 92.1: 22.04		NU159_YEAST (6-274): 2.61e-11: 68.5: 9.76