HitPredict

Interactor 1: VDAC1 (P21796)
Voltage-dependent anion-selective channel protein 1 (VDAC-1) (hVDAC1) (Outer mitochondrial membrane protein porin 1) (Plasmalemmal porin) (Porin 31HL) (Porin 31HM)
Gene: VDAC1

Interactor 2: SFXN1 (Q9H9B4)
Sideroflexin-1
Gene: SFXN1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	29128334, 29568061
Identification Methods	affinity chromatography technology, proximity labelling technology, cross-linking study
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005739 - mitochondrion
Homologous interactions	3

Homologous interactions

Color coding for hit scores

	1 283 Hs			1 322
+	Mm
		1141879 VDAC1_MOUSE (1-283): 9.77e-112: 326: 98.59		SFXN1_MOUSE (1-322): 0: 511: 94.72
+	Sc
		390000 VDAC1_YEAST (4-283): 7.73e-78: 239: 24.74		FSF1_YEAST (1-322): 2.05e-144: 411: 37.39
+	Hs
		330698 TOM40_HUMAN (4-279): 5.43e-60: 196: 12.46		SFXN5_HUMAN (7-322): 2.11e-141: 404: 37.15