HitPredict

Interactor 1: K0754 (O94854)
Microtubule-actin cross-linking factor 1, isoforms 6/7 (Uncharacterized protein KIAA0754)
Gene: MACF1

Interactor 2: RHOG (P84095)
Rho-related GTP-binding protein RhoG
Gene: RHOG

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005856 - cytoskeleton
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 3515 Hs			1 191
+	Hs
		319060 K0754_HUMAN (1-3515): 0: 1741: 100.00		RAC1_HUMAN (1-191): 1e-80: 239: 71.88
+	Hs
		319057 K0754_HUMAN (1-3515): 0: 1741: 100.00		RHOA_HUMAN (5-191): 2.01e-77: 231: 55.62
+	Hs
		319049 K0754_HUMAN (1-3515): 0: 1741: 100.00		RAC2_HUMAN (1-191): 3.6e-77: 230: 71.35
+	Hs
		319046 K0754_HUMAN (1-3515): 0: 1741: 100.00		RHOC_HUMAN (5-191): 1.31e-75: 226: 56.15
+	Hs
		319056 K0754_HUMAN (1-3515): 0: 1741: 100.00		RAC3_HUMAN (1-177): 2.18e-74: 223: 72.88
+	Hs
		1015372 SPTB2_HUMAN (1795-3334): 1.51e-60: 234: 14.62		RHOG_HUMAN (1-191): 1.42e-80: 239: 100.00
+	Hs
		988286 SPTB2_HUMAN (1795-3334): 1.51e-60: 234: 14.62		RAC1_HUMAN (1-191): 1e-80: 239: 71.88
+	Hs
		1015444 GOGB1_HUMAN (1405-3448): 2.88e-58: 227: 8.83		RHOG_HUMAN (1-191): 1.42e-80: 239: 100.00
+	Hs
		955068 SPTB2_HUMAN (1795-3334): 1.51e-60: 234: 14.62		CDC42_HUMAN (1-191): 2.01e-77: 231: 60.73
+	Hs
		961961 SPTB2_HUMAN (1795-3334): 1.51e-60: 234: 14.62		RHOA_HUMAN (5-191): 2.01e-77: 231: 55.62
+	Hs
		580995 SPTB2_HUMAN (1795-3334): 1.51e-60: 234: 14.62		RAC2_HUMAN (1-191): 3.6e-77: 230: 71.35
+	Hs
		466207 SPTB2_HUMAN (1795-3334): 1.51e-60: 234: 14.62		RHOC_HUMAN (5-191): 1.31e-75: 226: 56.15
+	Hs
		955179 GOGB1_HUMAN (1405-3448): 2.88e-58: 227: 8.83		CDC42_HUMAN (1-191): 2.01e-77: 231: 60.73
+	Hs
		962055 GOGB1_HUMAN (1405-3448): 2.88e-58: 227: 8.83		RHOA_HUMAN (5-191): 2.01e-77: 231: 55.62
+	Hs
		581055 GOGB1_HUMAN (1405-3448): 2.88e-58: 227: 8.83		RAC2_HUMAN (1-191): 3.6e-77: 230: 71.35
+	Hs
		953397 SPTB2_HUMAN (1795-3334): 1.51e-60: 234: 14.62		RAC3_HUMAN (1-177): 2.18e-74: 223: 72.88
+	Hs
		601243 SPTB2_HUMAN (1795-3334): 1.51e-60: 234: 14.62		RHOQ_HUMAN (4-189): 5.77e-73: 220: 56.84
+	Hs
		466256 GOGB1_HUMAN (1405-3448): 2.88e-58: 227: 8.83		RHOC_HUMAN (5-191): 1.31e-75: 226: 56.15
+	Hs
		953454 GOGB1_HUMAN (1405-3448): 2.88e-58: 227: 8.83		RAC3_HUMAN (1-177): 2.18e-74: 223: 72.88
+	Hs
		601292 GOGB1_HUMAN (1405-3448): 2.88e-58: 227: 8.83		RHOQ_HUMAN (4-189): 5.77e-73: 220: 56.84