Interactor 1: RPA2 (P22138)
DNA-directed RNA polymerase I subunit RPA135 (EC 2.7.7.6) (DNA-directed RNA polymerase I 135 kDa polypeptide) (A135) (DNA-directed RNA polymerase I polypeptide 2) (RNA polymerase I subunit 2)
Gene: RPA135

Interactor 2: RPA49 (Q01080)
DNA-directed RNA polymerase I subunit RPA49 (A49) (DNA-directed RNA polymerase I 49 kDa polypeptide)
Gene: RPA49

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.93 1.00 0.966

The method score is based on:

Property Details
Experiments 15477604, 22940862, 23209026, 9649439, 16554755, 16429126, 37968396, 24153184, 14759368
Identification Methods affinity chromatography technology, biochemical, x-ray crystallography, tandem affinity purification, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains RNA_pol_I_A49~RNA_pol_Rpb2_1, RNA_pol_I_A49~RNA_pol_Rpb2_6, RNA_pol_I_A49~RNA_pol_Rpb2_7
Common GO terms GO:0001054 - RNA polymerase I activity
GO:0003677 - DNA binding
GO:0005634 - nucleus
GO:0005736 - RNA polymerase I complex
GO:0006360 - transcription by RNA polymerase I
and 5 others

more...

Homologous interactions 5

Homologous interactions

Color coding for hit scores

1 1203
Sc

1 415
+ Hs
+ Mm
+ Hs
+ Hs
+ Hs

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Last updated: 15 Jul 2024