HitPredict

Interactor 1: FGFR3 (P22607)
Fibroblast growth factor receptor 3 (FGFR-3) (EC 2.7.10.1) (CD antigen CD333)
Gene: FGFR3

Interactor 2: DYN2 (P50570)
Dynamin-2 (EC 3.6.5.5) (Dynamin 2) (Dynamin II)
Gene: DNM2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	36736316
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	PH~PK_Tyr_Ser-Thr
Common GO terms	GO:0005794 - Golgi apparatus GO:0005886 - plasma membrane
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 806 Hs			1 870
+	Hs
		609615 FGFR3_HUMAN (10-806): 0: 819: 100.00		DYN3_HUMAN (1-870): 0: 994: 78.41
+	Hs
		384503 NTRK1_HUMAN (158-756): 5.97e-146: 450: 27.02		DYN2_HUMAN (1-870): 0: 1057: 100.00
+	Hs
		384691 NTRK1_HUMAN (158-756): 5.97e-146: 450: 27.02		DYN1_HUMAN (1-846): 0: 1002: 79.04
+	Hs
		128396 NTRK1_HUMAN (158-756): 5.97e-146: 450: 27.02		DNM1L_HUMAN (6-743): 0: 787: 39.13
+	Hs
		729628 VGFR2_HUMAN (5-342): 3.81e-17: 88.6: 16.58		DYN2_HUMAN (1-870): 0: 1057: 100.00
+	Hs
		507913 FGFR1_HUMAN (1-114): 1.97e-14: 79.4: 18.32		DYN2_HUMAN (1-870): 0: 1057: 100.00
+	Hs
		572603 VGFR1_HUMAN (40-357): 6.77e-13: 74.8: 13.25		DYN2_HUMAN (1-870): 0: 1057: 100.00
+	Hs
		601480 FGFR2_HUMAN (1-114): 9.04e-12: 70.9: 17.56		DYN2_HUMAN (1-870): 0: 1057: 100.00
+	Hs
		607921 FGFR4_HUMAN (1-130): 1.18e-11: 70.5: 19.31		DYN2_HUMAN (1-870): 0: 1057: 100.00
+	Hs
		508270 FGFR1_HUMAN (1-114): 1.97e-14: 79.4: 18.32		DYN3_HUMAN (1-870): 0: 994: 78.41
+	Hs
		601616 FGFR2_HUMAN (1-114): 9.04e-12: 70.9: 17.56		DYN3_HUMAN (1-870): 0: 994: 78.41
+	Hs
		608198 FGFR4_HUMAN (1-130): 1.18e-11: 70.5: 19.31		DYN3_HUMAN (1-870): 0: 994: 78.41