HitPredict

Interactor 1: IBP3 (P17936)
Insulin-like growth factor-binding protein 3 (IBP-3) (IGF-binding protein 3) (IGFBP-3)
Gene: IGFBP3

Interactor 2: IBP3 (P17936)
Insulin-like growth factor-binding protein 3 (IBP-3) (IGF-binding protein 3) (IGFBP-3)
Gene: IGFBP3

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 30184438
Identification Methods enzyme linked immunosorbent assay
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains IGFBP~Thyroglobulin_1, Thyroglobulin_1~Thyroglobulin_1
Common GO terms GO:0000165 - MAPK cascade
GO:0001558 - regulation of cell growth
GO:0001649 - osteoblast differentiation
GO:0001933 - negative regulation of protein phosphorylation
GO:0001968 - fibronectin binding
and 24 others

more...
Homologous interactions 12

Homologous interactions

Color coding for hit scores

1 291
Hs

1 291
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Dr

Service provided by Combinatics, Japan

Last updated: 11Aug2025