Protein: IBP6
Insulin-like growth factor-binding protein 6 (IBP-6) (IGF-binding protein 6) (IGFBP-6)

Gene: IBP6, IGFBP6
Organism: Homo sapiens
Interactions: 53
UniProt ID: P24592

Gene Ontology (top 5):
GO:0001968 - fibronectin binding
GO:0005102 - signaling receptor binding
GO:0005576 - extracellular region
GO:0005615 - extracellular space
GO:0007165 - signal transduction

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

377819

IGF2
Insulin-like growth factor 2

2

10

Small-scale

0.799

High

665911

IBP6
Insulin-like growth factor-binding protein 6

2

10

High-throughput

0.783

High

351503

FBLN4
EGF-containing fibulin-like extracellular matrix protein 2

2

16

High-throughput

0.606

High

665923

FBLN3
EGF-containing fibulin-like extracellular matrix protein 1

2

18

High-throughput

0.606

High

140145

SDCB1
Syntenin-1

2

0

High-throughput

0.580

High

353671

DRC4
Dynein regulatory complex subunit 4

2

0

High-throughput

0.580

High

665945

EPDR1
Mammalian ependymin-related protein 1

2

0

High-throughput

0.580

High

65334

TCAF2
TRPM8 channel-associated factor 2

2

1

High-throughput

0.574

High

665915

PP2BC
Serine/threonine-protein phosphatase 2B catalytic subunit gamma isoform

2

2

High-throughput

0.574

High

665940

CDK19
Cyclin-dependent kinase 19

2

1

High-throughput

0.558

High

665913

KRA59
Keratin-associated protein 5-9

2

10

High-throughput

0.553

High

665914

AQP1
Aquaporin-1

2

2

High-throughput

0.553

High

665918

KR108
Keratin-associated protein 10-8

2

9

High-throughput

0.553

High

665919

NCALD
Neurocalcin-delta

2

1

High-throughput

0.553

High

665922

CREB5
Cyclic AMP-responsive element-binding protein 5

2

1

High-throughput

0.553

High

665924

PO4F2
POU domain, class 4, transcription factor 2

2

1

High-throughput

0.553

High

665927

KRA57
Keratin-associated protein 5-7

2

10

High-throughput

0.553

High

665929

RBP10
Ran-binding protein 10

2

1

High-throughput

0.553

High

665933

ZN417
Zinc finger protein 417

2

1

High-throughput

0.553

High

665937

ZN587
Zinc finger protein 587

2

1

High-throughput

0.553

High

665941

ENKD1
Enkurin domain-containing protein 1

2

1

High-throughput

0.553

High

665944

UBQL2
Ubiquilin-2

2

6

High-throughput

0.553

High

665946

UBQL1
Ubiquilin-1

2

6

High-throughput

0.553

High

665921

PP2AA
Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform

1

1

High-throughput

0.536

High

518533

CALCB
Calcitonin gene-related peptide 2

1

0

High-throughput

0.513

High

287867

MYCB2
E3 ubiquitin-protein ligase MYCBP2

1

1

High-throughput

0.494

High

665943

UBQL4
Ubiquilin-4

1

6

High-throughput

0.494

High

665935

UBP7
Ubiquitin carboxyl-terminal hydrolase 7

1

2

High-throughput

0.489

High

665930

Q7Z6N9
CCDC28A protein

1

1

High-throughput

0.470

High

665947

X5D778
Ankyrin repeat domain 11 isoform A

1

2

High-throughput

0.470

High

665928

ANR11
Ankyrin repeat domain-containing protein 11

1

2

High-throughput

0.439

High

665931

CC28A
Coiled-coil domain-containing protein 28A

1

1

High-throughput

0.439

High

76421

B4DUB1
cyclin-dependent kinase

1

1

High-throughput

0.407

High

665920

CANB1
Calcineurin subunit B type 1

2

0

High-throughput

0.328

High

665939

PSMG3
Proteasome assembly chaperone 3

2

0

High-throughput

0.328

High

65870

MSGN1
Mesogenin-1

2

0

High-throughput

0.316

High

162159

CDIPT
CDP-diacylglycerol--inositol 3-phosphatidyltransferase

2

0

High-throughput

0.316

High

163411

MEIS2
Homeobox protein Meis2

2

0

High-throughput

0.316

High

223982

GET3
ATPase GET3

2

0

High-throughput

0.316

High

226704

SGTA
Small glutamine-rich tetratricopeptide repeat-containing protein alpha

2

0

High-throughput

0.316

High

352075

MBD3
Methyl-CpG-binding domain protein 3

2

0

High-throughput

0.316

High

426050

PPB1
Alkaline phosphatase, placental type

2

0

High-throughput

0.316

High

665916

MCSP
Sperm mitochondrial-associated cysteine-rich protein

2

0

High-throughput

0.316

High

665917

PGTB2
Geranylgeranyl transferase type-2 subunit beta

2

0

High-throughput

0.316

High

665926

PKHA7
Pleckstrin homology domain-containing family A member 7

2

0

High-throughput

0.316

High

665932

CC116
Coiled-coil domain-containing protein 116

2

0

High-throughput

0.316

High

665936

CA074
UPF0739 protein C1orf74

2

0

High-throughput

0.316

High

665938

UBAC1
Ubiquitin-associated domain-containing protein 1

2

0

High-throughput

0.316

High

665912

CCNC
Cyclin-C

1

0

High-throughput

0.279

Low

665925

PSMG4
Proteasome assembly chaperone 4

1

0

High-throughput

0.279

Low

665934

TP4AP
Short transient receptor potential channel 4-associated protein

1

0

High-throughput

0.279

Low

665942

AGO4
Protein argonaute-4

1

0

High-throughput

0.279

Low


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Last updated: 11Aug2025