HitPredict

Interactor 1: ROA2 (P22626)
Heterogeneous nuclear ribonucleoproteins A2/B1 (hnRNP A2/B1)
Gene: HNRNPA2B1

Interactor 2: NONO (Q15233)
Non-POU domain-containing octamer-binding protein (NonO protein) (54 kDa nuclear RNA- and DNA-binding protein) (p54(nrb)) (p54nrb) (55 kDa nuclear protein) (NMT55) (DNA-binding p52/p100 complex, 52 kDa subunit)
Gene: NONO

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	37071682
Identification Methods	cross-linking study
Interaction Type	physical association

Property	Details
Interacting Pfam domains	NOPS~RRM_1, RRM_1~RRM_1
Common GO terms	GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0006397 - mRNA processing GO:0016020 - membrane and 1 others more... GO:0016363 - nuclear matrix
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 353 Hs			1 471
+	Hs
		162056 HNRDL_HUMAN (12-292): 9.81e-66: 215: 33.45		NONO_HUMAN (1-471): 1.15e-97: 303: 100.00
+	Hs
		162035 HNRDL_HUMAN (12-292): 9.81e-66: 215: 33.45		PABP4_HUMAN (66-467): 1.55e-70: 237: 15.42
+	Hs
		162097 HNRDL_HUMAN (12-292): 9.81e-66: 215: 33.45		PSPC1_HUMAN (20-470): 2.17e-67: 226: 58.41
+	Hs
		161948 HNRDL_HUMAN (12-292): 9.81e-66: 215: 33.45		PABP1_HUMAN (66-459): 7.11e-65: 222: 14.89
+	Hs
		609971 ROA2_HUMAN (1-353): 9.07e-61: 200: 100.00		PSPC1_HUMAN (20-470): 2.17e-67: 226: 58.41
+	Hs
		516358 ROA2_HUMAN (1-353): 9.07e-61: 200: 100.00		PABP1_HUMAN (66-459): 7.11e-65: 222: 14.89
+	Hs
		609715 ROA2_HUMAN (1-353): 9.07e-61: 200: 100.00		SFPQ_HUMAN (45-471): 3.15e-53: 192: 56.92
+	Hs
		162059 HNRDL_HUMAN (12-292): 9.81e-66: 215: 33.45		ELAV1_HUMAN (68-205): 7.38e-47: 166: 27.82
+	Hs
		1031404 PABP4_HUMAN (19-200): 1.59e-38: 146: 19.67		PSPC1_HUMAN (20-470): 2.17e-67: 226: 58.41
+	Hs
		609862 ROA2_HUMAN (1-353): 9.07e-61: 200: 100.00		ELAV3_HUMAN (54-270): 2.36e-48: 171: 22.46
+	Hs
		516495 PABP4_HUMAN (19-200): 1.59e-38: 146: 19.67		PABP1_HUMAN (66-459): 7.11e-65: 222: 14.89
+	Hs
		609883 ROA2_HUMAN (1-353): 9.07e-61: 200: 100.00		ELAV1_HUMAN (68-205): 7.38e-47: 166: 27.82
+	Hs
		516339 PABP1_HUMAN (12-200): 2.75e-37: 143: 18.95		PABP1_HUMAN (66-459): 7.11e-65: 222: 14.89
+	Hs
		1031344 PABP4_HUMAN (19-200): 1.59e-38: 146: 19.67		ELAV1_HUMAN (68-205): 7.38e-47: 166: 27.82
+	Hs
		609833 ROA2_HUMAN (1-353): 9.07e-61: 200: 100.00		ELAV2_HUMAN (150-210): 9.69e-14: 74.5: 25.81
+	Hs
		201707 MSI1H_HUMAN (3-341): 3.78e-60: 199: 28.77		RBM4B_HUMAN (75-182): 7.1e-09: 59.3: 35.71
+	Hs
		474021 PABP4_HUMAN (19-200): 1.59e-38: 146: 19.67		PAB4L_HUMAN (139-369): 5.62e-18: 87.3: 14.09
+	Hs
		1020249 PABP4_HUMAN (19-200): 1.59e-38: 146: 19.67		ELAV2_HUMAN (150-210): 9.69e-14: 74.5: 25.81
+	Hs
		516484 PABP1_HUMAN (12-200): 2.75e-37: 143: 18.95		ELAV2_HUMAN (150-210): 9.69e-14: 74.5: 25.81