Protein: IBP4
Insulin-like growth factor-binding protein 4 (IBP-4) (IGF-binding protein 4) (IGFBP-4)

Gene: IBP4, IGFBP4
Organism: Homo sapiens
Interactions: 47
UniProt ID: P22692

Gene Ontology (top 5):
GO:0000165 - MAPK cascade
GO:0001558 - regulation of cell growth
GO:0005102 - signaling receptor binding
GO:0005576 - extracellular region
GO:0005615 - extracellular space

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

420274

IGF1
Insulin-like growth factor 1

4

10

Small-scale

0.909

High

377818

IGF2
Insulin-like growth factor 2

3

10

Small-scale

0.849

High

504706

FBSP1
F-box/SPRY domain-containing protein 1

2

3

High-throughput

0.601

High

181610

CETN3
Centrin-3

2

1

High-throughput

0.549

High

287864

MYCB2
E3 ubiquitin-protein ligase MYCBP2

2

1

High-throughput

0.549

High

651597

KLH22
Kelch-like protein 22

2

4

High-throughput

0.549

High

651600

MEGF8
Multiple epidermal growth factor-like domains protein 8

2

20

High-throughput

0.549

High

651605

SPRY3
SPRY domain-containing protein 3

2

1

High-throughput

0.549

High

562695

BMP1
Bone morphogenetic protein 1

1

4

High-throughput

0.536

High

651594

NOTC1
Neurogenic locus notch homolog protein 1

1

9

High-throughput

0.536

High

651596

NOTC2
Neurogenic locus notch homolog protein 2

1

6

High-throughput

0.536

High

651604

VWDE
von Willebrand factor D and EGF domain-containing protein

1

8

High-throughput

0.536

High

650050

FGFR3
Fibroblast growth factor receptor 3

1

2

High-throughput

0.515

High

651593

BAG6
Large proline-rich protein BAG6

1

5

High-throughput

0.515

High

651606

I17RA
Interleukin-17 receptor A

1

0

High-throughput

0.513

High

160683

TOR1A
Torsin-1A

1

0

High-throughput

0.493

High

301342

WFS1
Wolframin

1

0

High-throughput

0.493

High

442235

GELS
Gelsolin

1

0

High-throughput

0.493

High

651590

GRN
Progranulin

1

0

High-throughput

0.493

High

651598

KLH26
Kelch-like protein 26

1

4

High-throughput

0.489

High

651602

P3H3
Prolyl 3-hydroxylase 3

1

1

High-throughput

0.489

High

651603

UBR2
E3 ubiquitin-protein ligase UBR2

1

1

High-throughput

0.489

High

651607

NUD12
NAD-capped RNA hydrolase NUDT12

1

1

High-throughput

0.489

High

651608

KLHL9
Kelch-like protein 9

1

4

High-throughput

0.489

High

651609

KLH13
Kelch-like protein 13

1

4

High-throughput

0.489

High

217836

TGON2
Trans-Golgi network integral membrane protein 2

1

6

High-throughput

0.479

High

287527

LRP6
Low-density lipoprotein receptor-related protein 6

1

4

Small-scale

0.479

High

468075

HS90B
Heat shock protein HSP 90-beta

1

2

High-throughput

0.479

High

552502

IMDH2
Inosine-5'-monophosphate dehydrogenase 2

1

1

High-throughput

0.479

High

109368

G5E9A7
DM1 locus, WD repeat containing

1

2

High-throughput

0.470

High

167226

KLF11
Krueppel-like factor 11

1

2

High-throughput

0.470

High

245869

KIF1B
Kinesin-like protein KIF1B

1

1

High-throughput

0.470

High

651599

SPRE1
Sprouty-related, EVH1 domain-containing protein 1

1

1

High-throughput

0.470

High

451600

GPX1
Glutathione peroxidase 1

1

2

High-throughput

0.407

High

651601

LONP2
Lon protease homolog 2, peroxisomal

2

0

High-throughput

0.313

High

651611

NISCH
Nischarin

1

0

High-throughput

0.279

Low

651612

SBDS
Ribosome maturation protein SBDS

1

0

High-throughput

0.279

Low

47306

A0A6Q8PF08
Peripheral myelin protein 22

1

0

High-throughput

0.268

Low

651592

HD
Huntingtin

1

0

High-throughput

0.268

Low

651595

ATX3
Ataxin-3

1

0

High-throughput

0.268

Low

216376

SUV91
Histone-lysine N-methyltransferase SUV39H1

1

0

High-throughput

0.265

Low

246432

KDM1A
Lysine-specific histone demethylase 1A

1

0

High-throughput

0.265

Low

302375

RNF8
E3 ubiquitin-protein ligase RNF8

1

0

Small-scale

0.249

Low

651589

RL13
Large ribosomal subunit protein eL13

1

0

High-throughput

0.249

Low

651591

RL3
Large ribosomal subunit protein uL3

1

0

High-throughput

0.249

Low

322580

FBX21
F-box only protein 21

1

0

High-throughput

0.232

Low

651610

FBX3
F-box only protein 3

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025